2024 article

Evaluation of Adjuvant Effect of Cytosine-Guanosine-Oligodeoxynucleotide in Meat-Type Chickens Coadministered <i>In Ovo</i> with Herpesvirus of Turkey Vaccine

Boone, A. C., Kulkarni, R. R., Cortes, A. L., Gaghan, C., Mohammed, J., Villalobos, T., … Gimeno, I. M. (2024, February 1). VIRAL IMMUNOLOGY, Vol. 2.

By: A. Boone n, R. Kulkarni  n, A. Cortes n, C. Gaghan n, J. Mohammed*, T. Villalobos*, J. Esandi*, I. Gimeno n 

author keywords: herpesvirus of turkey; toll-like receptor 21; cellular immunity; immunocompetence; in ovo vaccination; chickens
TL;DR: Adding cytosine-guanosine oligodeoxynucleotides (CpG ODNs) to the HVT vaccine could enhance the adjuvant effect of HVT, and CpG ODN administration in ovo with or without HVT significantly increased frequencies of activated CD4+ and CD8+ T cells. (via Semantic Scholar)
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Added: February 12, 2024

Herpesvirus of turkey (HVT) increases activation of T cells in 1-day-old chickens when administered