2024 journal article

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Serum binding folate receptor autoantibodies lower in autistic boys and positively-correlated with folate

BIOMEDICINE & PHARMACOTHERAPY, 172.

By: A. Shi ^*, D. Liu ^*, H. Wu ^*, R. Zhu ^*, Y. Deng ^*, L. Yao^*, Y. Xiao ^*, G. Lorimer ^* ...and 5 other authors, including 1 NC State author, R. Ghiladi ⁿ , X. Xu ^*, R. Zhang ^*, H. Xu^* & J. Wang ^*

author keywords: Autism; Folate receptor autoantibody; Folate; Ferritin; VB12

TL;DR: Differences revealed that the low serum FRAA in autistic children was mediated by multiple factors, which deserves more comprehensive investigation with larger population and mechanistic studies. (via Semantic Scholar)

10.1016/j.biopha.2024.116191

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open access via doi.org (publisher)

UN Sustainable Development Goal Categories

2. Zero Hunger (OpenAlex)

3. Good Health and Well-being (Web of Science)

Source: Web Of Science

Added: March 25, 2024

Folate receptor autoantibody (FRAA) has caught increasing attention since its discovery in biological fluids of patients with autism spectrum disorder (ASD), but quantification and understanding of its function are still in their infancy. In this study, we aimed to quantify serum binding-FRAA and explore its relation with serum folate, vitamin B