2019 journal article

Effect of pseudomonas lipase enzyme on the degradation of polycaprolactone/polycaprolactone-polyglycolide fiber blended nanocomposites

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 68(7), 360–367.

By: S. Spearman*, F. Irin*, S. Ramesh*, I. Rivero*, M. Green* & O. Harrysson n

co-author countries: United States of America 🇺🇸
Source: Web Of Science
Added: April 22, 2019

This study describes the interaction resulting from adding pseudomonas lipase (PS) enzyme to polycaprolactone-based composites designed for orthopedic applications. The biopolymer composite evaluated in this study consists of electrospun polycaprolactone (PCL)/polyglycolide (PGA) blended fibers impregnated with double stranded deoxyribonucleic acid wrapped single-walled carbon nanotubes encapsulated by a PCL matrix. PS enzyme was used to catalyze the degradation of PCL-based biocomposites. PCL present in the biocomposites showed considerable degradation in 4 weeks in the presence of the enzyme, exhibiting a contrast to hydrolytic degradation which lasts several years. PGA-consisting fibers degraded completely within one week of exposure to the enzyme.