Vangl2 coordinates cell rearrangements during gut elongation
DEVELOPMENTAL DYNAMICS, 248(7), 569–582.
author keywords: Vangl2; endoderm; gut; Xenopus; morphogenesis; elongation
MeSH headings : Animals; Body Patterning; Cell Adhesion; Cell Movement; Cell Polarity; Endoderm / cytology; Intestines / anatomy & histology; Intestines / growth & development; Membrane Proteins / metabolism; Membrane Proteins / physiology; Morphogenesis; Xenopus Proteins / metabolism; Xenopus Proteins / physiology; Xenopus laevis / growth & development
TL;DR:
The embryonic gut tube undergoes extensive lengthening to generate the surface area required for nutrient absorption across the digestive epithelium in Xenopus, a process that concomitantly opens the gut lumen and facilitates epithelial morphogenesis.
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