DendriPeps: Expanding Dendrimer Functionality by Hybridizing Poly(amidoamine) (PAMAM) Scaffolds with Peptide Segments
MACROMOLECULAR RAPID COMMUNICATIONS, 40(22).
author keywords: internally functionalized dendrimers; orthogonal protection strategies; poly(amidoamine); polymer-peptide chemistry
MeSH headings : Amino Acids / chemistry; Dendrimers / chemistry; Dendrimers / metabolism; Drug Delivery Systems / methods; Molecular Dynamics Simulation; Molecular Structure; Peptides / chemistry; Peptides / metabolism; Tissue Scaffolds / chemistry
TL;DR:
The precise control over the number, type, and topological placement of functional groups expands the functional behavior of DendriPeps beyond current PAMAM dendrimers toward new frontiers or colloids, drug delivery vectors, and catalysis.
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