2020 journal article
International lineages of Salmonella enterica serovars isolated from chicken farms, Wakiso District, Uganda
PLOS ONE, 15(1).
MeSH headings : Animals; Anti-Bacterial Agents / classification; Anti-Bacterial Agents / pharmacology; Chickens / microbiology; Drug Resistance, Multiple, Bacterial / genetics; Farms; Genes, Bacterial; Humans; Immunologic Surveillance; Plasmids / chemistry; Plasmids / metabolism; Poultry Diseases / epidemiology; Poultry Diseases / microbiology; Poultry Diseases / transmission; Prevalence; Replicon; Salmonella Infections / epidemiology; Salmonella Infections / microbiology; Salmonella Infections / transmission; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Seasons; Uganda / epidemiology; Whole Genome Sequencing
TL;DR:
It is concluded that MDR Salmonella highlights the risks posed to the animals, environment, and humans for infection and implementing a robust integrated surveillance system in Uganda will help monitor MDR to help control infectious threats.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 15, 2020
The growing occurrence of multidrug-resistant (MDR) Salmonella enterica in poultry has been reported with public health concern worldwide. We reported, recently, the occurrence of Escherichia coli and Salmonella enterica serovars carrying clinically relevant resistance genes in dairy cattle farms in the Wakiso District, Uganda, highlighting an urgent need to monitor food-producing animal environments. Here, we present the prevalence, antimicrobial resistance, and sequence type of 51 Salmonella isolates recovered from 400 environmental samples from chicken farms in Uganda. Among the Salmonella isolates, 32/51 (62.7%) were resistant to at least one antimicrobial, and 10/51 (19.6%) displayed multiple drug resistance. Through PCR, five replicon plasmids were identified among all chicken Salmonella including IncFIIS 17/51 (33.3%), IncI1α 12/51 (23.5%), IncP 8/51 (15.7%), IncX1 8/51 (15.7%), and IncX2 1/51 (2.0%). In addition, we identified replicons through WGS (ColpVC and IncFIB). A significant seasonal difference between chicken sampling periods was observed (p= 0.0017). We conclude that MDR Salmonella highlights the risks posed to the animals, environment, and humans for infection. Implementing a robust integrated surveillance system in Uganda will help monitor MDR to help control infectious threats.