Mechanical competition alters the cellular interpretation of an endogenous genetic programme
Bhide, S., Gombalova, D., Mönke, G., Stegmaier, J., Zinchenko, V., Kreshuk, A., … Leptin, M. (2020, October 15). (Vol. 10). Vol. 10.
TL;DR:
It is shown here that tissue-wide interactions force these cells to expand even when an otherwise sufficient amount of apical, active actomyosin is present, and models show that this behaviour is a general emergent property of actomyOSin networks [in a supracellular context, in accordance with experimental observations of actin reorganisation within stretching cells.
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