2021 journal article

A promising Ames battery for mutagenicity characterization of new dyes

ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 62(1), 52–65.

By: G. Umbuzeiro n, D. Morales*, F. Vacchi*, A. Albuquerque*, M. Szymczyk n, X. Sui n, N. Vinueza n, H. Freeman n

author keywords: anthraquinones; azo dyes; microplate agar; Salmonella; microsome assay
MeSH headings : Coloring Agents / adverse effects; Coloring Agents / chemistry; Molecular Conformation; Mutagenesis / drug effects; Mutagenicity Tests / methods; Mutagens / adverse effects; Mutagens / chemistry; Salmonella typhimurium / drug effects; Salmonella typhimurium / genetics; Solubility
TL;DR: It is proposed that dyes should be tested in a tiered approach using YG1041 followed by TA97a, TA98, and TA100 in concentration‐response experiments, which provides additional information on the dye mutagenicity database available in the literature. (via Semantic Scholar)
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Source: Web Of Science
Added: January 4, 2021

Abstract