2021 review

Evaluating Use Cases for Human Challenge Trials in Accelerating SARS-CoV-2 Vaccine Development

[Review of ]. CLINICAL INFECTIOUS DISEASES, 72(4), 710–715.

By: L. Nguyen*, C. Bakerlee*, T. McKelvey, S. Rose*, A. Norman, N. Joseph*, D. Manheim*, M. McLaren n ...

author keywords: vaccine evaluation; COVID-19; pandemic; controlled human infection; human challenge trial
MeSH headings : COVID-19; COVID-19 Vaccines; Clinical Trials as Topic; Humans; Pandemics; SARS-CoV-2
TL;DR: It is found that HCTs are likely to be most useful for vaccine candidates currently in preclinical stages of development, and that, while currently limited in their application, there are scenarios in which H CTs would be extremely beneficial. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 10, 2021

Abstract