2021 article

Biofabricated 3D in vitro model of fibrosis-induced abnormal hepatoblast/biliary progenitors' expansion of the developing liver

Brovold, M., Keller, D., Devarasetty, M., Dominijanni, A., Shirwaiker, R., & Soker, S. (2021, June 5). BIOENGINEERING & TRANSLATIONAL MEDICINE.

By: M. Brovold*, D. Keller*, M. Devarasetty*, A. Dominijanni*, R. Shirwaiker n  & S. Soker *

author keywords: 3D organoids; biliary development; fibrosis; HepaRG; hepatic stellate cell
TL;DR: A simple yet robust model that recapitulates physico‐mechanical and cellular aspects of fibrosis mediated via hepatic stellate cells (HSCs) and their effects on biliary progenitor cells is developed to benefit pediatric patients that suffer from the biliary dysgenesis associated with a multitude of congenital liver diseases. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 14, 2021

Abstract