2021 journal article

Preparation of substituted alkoxypyridines via directed metalation and metal-halogen exchange

ARKIVOC, 57–72.

By: I. Bori n & D. Comins n

author keywords: Alkoxypyridines; directed metalation; metal-halogen exchange; halogen dance reactions
Source: Web Of Science
Added: June 21, 2021

Several halo-substituted alkoxypyridines were prepared and subjected to directed metalation and metal-halogen exchange reactions. The studies resulted in useful methods for synthesis of numerous substituted pyridines via regioselective lithiation, magnesation and halogen dance reactions