2021 journal article

Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia

INFECTIOUS AGENTS AND CANCER, 16(1).

By: C. Bosire *, A. Vidal*, J. Smith *, D. Jima n, Z. Huang *, D. Skaar n , F. Valea *, R. Bentley * ...

author keywords: Cervical intraepithelial neoplasia; Gene methylation; Imprinted gene; Human papillomavirus
TL;DR: An association between altered DNA methylation at regulatory regions of PEG3 and high grade CIN in high-risk HPV positive cases is suggested in women enrolled at colposcopic evaluation. (via Semantic Scholar)
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Added: June 28, 2021

Epigenetic mechanisms are hypothesized to contribute substantially to the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer, although empirical data are limited.