2021 article

Cytoskeletal biophysics: Passive crosslinker adapts to keep microtubule bundles on track

Elting, M. W. (2021, June 21). CURRENT BIOLOGY, Vol. 31, pp. R793–R796.

By: M. Elting n

MeSH headings : Biophysics; Microtubules; Spindle Apparatus
Source: Web Of Science
Added: July 6, 2021

Assembly of the mitotic spindle requires dynamic adaptation and coordination among an array of motors and crosslinkers. A new study demonstrates in vitro how the mitotic crosslinker PRC1 can tune its behavior to regulate the speed of microtubule sliding.