The Cyanotoxin 2,4-DAB Reduces Viability and Causes Behavioral and Molecular Dysfunctions Associated with Neurodegeneration in Larval Zebrafish
Neurotoxicity Research, 40(2), 347–364.
author keywords: Cyanotoxins; Mixtures; 2,4-DAB; Zebrafish; Behavior; Proteomics
MeSH headings : Amino Acids, Diamino / toxicity; Animals; Cyanobacteria; Cyanobacteria Toxins; Isomerism; Larva; Neurotoxicity Syndromes; Neurotoxins / toxicity; Zebrafish
TL;DR:
Together, the data demonstrate that BMAA and its isomers AEG and 2,4-DAB cause neurotoxic effects in vivo, with 2, 4- DAB as the most potent of the three in the zebrafish model.
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