2022 journal article
Close encounters in the corn field
Molecular Plant, 2.
Plants defend themselves against microbial pathogens in several ways. Among the most important of these mechanisms are cytoplasmic nucleotide-binding, leucine-rich repeat (NLR) resistance (R) proteins that are activated by direct or indirect interaction with pathogen-derived effector proteins introduced into the plant cell as part of the pathogenesis process. Effectors that trigger NLR-mediated resistance are known as Avirulence (Avr) proteins. The two major classes of NLR proteins are differentiated by their N-terminal domains being either coiled-coil (CC) or Toll/interleukin-1 receptor (TIR) domains.