2022 article

Prevalence of aldosterone breakthrough in dogs receiving renin-angiotensin system inhibitors for proteinuric chronic kidney disease

Ames, M. K., Vaden, S. L., Atkins, C. E., Palerme, J.-S., Langston, C. E., Grauer, G. F., … Webb, T. (2022, November 9). JOURNAL OF VETERINARY INTERNAL MEDICINE.

author keywords: mineralocorticoid receptor antagonists; nephrology; renin-angiotensin-aldosterone system; urine aldosterone to creatinine ratio
MeSH headings : Dogs; Animals; Aldosterone; Renin-Angiotensin System / physiology; Creatinine / urine; Prospective Studies; Prevalence; Antihypertensive Agents / therapeutic use; Proteinuria / drug therapy; Proteinuria / veterinary; Renal Insufficiency, Chronic / drug therapy; Renal Insufficiency, Chronic / veterinary; Dog Diseases / drug therapy
TL;DR: Whether ABT occurs in dogs with CKDP and if it is associated with decreased efficacy in proteinuria reduction during RAS inhibitor treatment is investigated and its relationship with outcomes is evaluated. (via Semantic Scholar)
Source: Web Of Science
Added: November 21, 2022

Abstract