2022 journal article

Imp2p forms actin-dependent clusters and imparts stiffness to the contractile ring

MOLECULAR BIOLOGY OF THE CELL, 33(14).

By: K. Bellingham-Johnstun n, B. Commer  n, B. Levesque n, Z. Tyree n & C. Laplante n

MeSH headings : Actin Cytoskeleton / metabolism; Actins / metabolism; Cytokinesis; Schizosaccharomyces / metabolism; Schizosaccharomyces pombe Proteins / metabolism
TL;DR: It is found that similarly to Cdc15p, Imp2p contributes to the stiffness of the contractile ring and assembles into protein clusters, indicating that the two proteins influence each other during cytokinesis, which may partially explain their similar phenotypes. (via Semantic Scholar)
Source: Web Of Science
Added: January 3, 2023

The contractile ring must anchor to the plasma membrane and cell wall to transmit its tension. We combine single molecule localization microscopy and laser ablation to reveal the molecular organization of Imp2p, a putative protein anchor, and its role in the mechanical properties of the contractile ring.