2022 article

Long-term effects of ciclosporin and oclacitinib on mediators of tolerance, regulatory T-cells, IL-10 and TGF-beta, in dogs with atopic dermatitis

Herrmann, I., Mamo, L. B., Holmes, J., Mohammed, J. P., Murphy, K. M., & Bizikova, P. (2022, December 8). VETERINARY DERMATOLOGY.

By: I. Herrmann n, L. Mamo n, J. Holmes n, J. Mohammed n, K. Murphy n & P. Bizikova n

author keywords: canine atopic dermatitis; ciclosporin; oclacitinib; T regulatory cell
MeSH headings : Dogs; Animals; Cyclosporine / therapeutic use; T-Lymphocytes, Regulatory; Interleukin-10; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Transforming Growth Factor beta1 / therapeutic use; Transforming Growth Factor beta / therapeutic use; Immune Tolerance; Dog Diseases / drug therapy
TL;DR: Lower Treg cell percentages in the CSA-treated dogs suggest an impact of this drug on this cell population; however, it does not necessarily mean that it diminishes tolerance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 3, 2023

Abstract