@article{galik_latta_gambino_2019, title={Piecemeal or combined? Assessing greenhouse gas mitigation spillovers in US forest and agriculture policy portfolios}, volume={19}, ISSN={["1752-7457"]}, url={https://doi.org/10.1080/14693062.2019.1663719}, DOI={10.1080/14693062.2019.1663719}, abstractNote={ABSTRACT Forest and agricultural sector response to comprehensive climate policy is well represented in the literature. Less analysis has been devoted to piecemeal solutions. We use the Forest and Agriculture Sector Optimization Model with Greenhouse Gases (FASOMGHG) to project the individual and combined effect of three existing U.S. Department of Agriculture programmes with potential to increase greenhouse gas (GHG) mitigation. We find that a combined policy scenario may achieve greater mitigation than individual constituent programmes, suggesting the possibility of complementary spillover effects in some periods. Mitigation varies over time, however, and some periods experience net emissions as markets and management practices respond to initial policy shocks. The regional distribution of GHG mitigation also varies between policy scenario. Differences in the magnitude and imputed cost of mitigation under each scenario, generating negative values for some programmes and time periods, reinforces the need to evaluate portfolio design to cost-effectively achieve near-term GHG mitigation. Key policy insights Increased near-term GHG mitigation in the forest and agriculture sectors in the US may be possible by expanding or refocusing the emphasis of existing programmes. Implementing several such forest and agricultural programmes simultaneously may lead to greater GHG mitigation than when implemented separately, indicating the possibility of positive spillover effects. Programmes targeted to agricultural management may hold outsized potential to achieve near-term GHG mitigation; Policies aimed at influencing land use conversion appear to be more vulnerable to reversion and subject to larger inter-annual swings. The staged implementation of programmes could also be useful, helping to encourage increased mitigation (or the retention of already achieved mitigation) over time as markets re-equilibrate to initial shocks. Though the particular scenarios assessed here are unique to the US, our findings may be applicable to other locations outside the US where land management is influenced by individual market actors and there is competition between forest and agricultural land uses.}, number={10}, journal={CLIMATE POLICY}, publisher={Informa UK Limited}, author={Galik, Christopher S. and Latta, Gregory S. and Gambino, Christopher}, year={2019}, month={Nov}, pages={1270–1283} } @article{huigens_ma_gambino_moeller_basso_cavanagh_wozniak_melander_2008, title={Control of bacterial biofilms with marine alkaloid derivatives}, volume={4}, ISSN={["1742-2051"]}, DOI={10.1039/b719989a}, abstractNote={Bacterial biofilms are defined as a community of surface-attached bacteria that are protected by an extracellular matrix of biomolecules. We have recently reported the synthesis of a small molecule, denoted TAGE, based on the natural product bromoageliferin and demonstrated that TAGE has anti-biofilm activity against Pseudomonas aeruginosa. Herein we demonstrate that TAGE: (1) does not have selective toxicity against cells within the biofilm state, (2) will inhibit biofilm development under flow conditions, indicating that the CV staining protocol correlates with the ability to be active under biomimetic conditions, and (3) will disperse preformed P. aeruginosa biofilms. We also present preliminary toxicity work that indicates that TAGE is devoid of cytotoxicity in rat and mice cell lines. Advanced derivatives of TAGE have generated compounds shown to be exceedingly effective as biofilm inhibitors against the gamma-proteobacteria in this study (P. aeruginosa strains PAO1, PA14, PDO300, and Acinetobacter baumannii). TAGE derivatives also possessed anti-biofilm activity against the beta-proteobacterium Bordetella bronchiseptica (Rb50) and the Gram-positive bacterium Staphylococcus aureus;TAGE derivatives inhibited the formation of biofilms, however, some of this activity is attributed to microbicidal activity. The TAGE derivatives presented in this study, however, do not disperse pre-formed biofilms with the same efficiency as TAGE.}, number={6}, journal={MOLECULAR BIOSYSTEMS}, author={Huigens, Robert W., III and Ma, Luyan and Gambino, Christopher and Moeller, Peter D. R. and Basso, Anne and Cavanagh, John and Wozniak, Daniel J. and Melander, Christian}, year={2008}, pages={614–621} }