@article{wang_dhawan_du_batchelor_leonard_misra_vo-dinh_2013, title={Molecular sentinel-on-chip for SERS-based biosensing}, volume={15}, ISSN={["1463-9076"]}, DOI={10.1039/c3cp00076a}, abstractNote={The development of DNA detection techniques on large-area plasmonics-active platforms is critical for many medical applications such as high-throughput screening, medical diagnosis and systems biology research. Here, we report for the first time a unique "molecular sentinel-on-chip" (MSC) technology for surface-enhanced Raman scattering (SERS)-based DNA detection. This unique approach allows label-free detection of DNA molecules on chips developed on a wafer scale using large area nanofabrication methodologies. To develop plasmonics-active biosensing platforms in a repeatable and reproducible manner, we employed a combination of deep UV lithography, atomic layer deposition, and metal deposition to fabricate triangular-shaped nanowire (TSNW) arrays having controlled sub-10 nm gap nanostructures over an entire 6 inch wafer. The detection of a DNA sequence of the Ki-67 gene, a critical breast cancer biomarker, on the TSNW substrate illustrates the usefulness and potential of the MSC technology as a novel SERS-based DNA detection method.}, number={16}, journal={PHYSICAL CHEMISTRY CHEMICAL PHYSICS}, author={Wang, Hsin-Neng and Dhawan, Anuj and Du, Yan and Batchelor, Dale and Leonard, Donovan N. and Misra, Veena and Vo-Dinh, Tuan}, year={2013}, pages={6008–6015} }
 @article{dhawan_du_batchelor_wang_leonard_misra_ozturk_gerhold_vo-dinh_2011, title={Hybrid Top-Down and Bottom-Up Fabrication Approach for Wafer-Scale Plasmonic Nanoplatforms}, volume={7}, ISSN={["1613-6810"]}, DOI={10.1002/smll.201002186}, abstractNote={Bridging the nanoscale level of probe fabrication and the megascale dimensions of sensor systems is one of the greatest challenges in the development of large-area plasmonic sensing platforms. We report a generalized hybrid nanofabrication approach combining top-down (deep-UV lithography) and bottom-up (controlled lateral epitaxial growth and atomic layer deposition) fabrication techniques for the development of nanostructured platforms. This technology allows the development of reproducible substrates with controlled sub-10 nm gaps between plasmonic nanostructures over an entire 6 inch wafer (1 inch ≈ 2.54 cm). By integrating soft matter (DNA probes) and hard matter (silicon nanochips), these}, number={6}, journal={SMALL}, author={Dhawan, Anuj and Du, Yan and Batchelor, Dale and Wang, Hsin-Neng and Leonard, Donovon and Misra, Veena and Ozturk, Mehmet and Gerhold, Michael D. and Vo-Dinh, Tuan}, year={2011}, month={Mar}, pages={727–731} }
 @article{dhawan_du_yan_gerhold_misra_vo-dinh_2010, title={Methodologies for Developing Surface-Enhanced Raman Scattering (SERS) Substrates for Detection of Chemical and Biological Molecules}, volume={10}, ISSN={["1558-1748"]}, DOI={10.1109/jsen.2009.2038634}, abstractNote={This paper describes methodologies for developing efficient surface-enhanced Raman scattering (SERS) substrates such as annealing thin gold films for developing gold nanoislands, fabrication of nanopillars arrays and roughened films by employing focused ion beam (FIB) milling of gold films, as well as overcoating deep-UV-fabricated silicon nanowires with a layer of gold film. Excitation of surface plasmons in these gold nanostructures leads to substantial enhancement in the Raman scattering signal obtained from molecules lying in the vicinity of the nanostructure surface. In this paper, we perform comparative studies of SERS signals from molecules such as p-mercaptobenzoic acid and cresyl fast violet attached to or adsorbed on various gold SERS substrates. It was observed that gold-coated silicon nanowire substrates and annealed gold island substrates provided considerably higher SERS signals as compared to those from the FIB patterned substrates and planar gold films. The SERS substrates developed by the different processes were employed for detection of biological molecules such as dipicolinic acid, an excellent marker for spores of bacteria such as Anthrax.}, number={3}, journal={IEEE SENSORS JOURNAL}, author={Dhawan, Anuj and Du, Yan and Yan, Fei and Gerhold, Michael D. and Misra, Veena and Vo-Dinh, Tuan}, year={2010}, month={Mar}, pages={608–616} }
 @article{luo_du_misra_2008, title={Large area nanorings fabricated using an atomic layer deposition Al(2)O(3) spacer for magnetic random access memory application}, volume={19}, ISSN={["0957-4484"]}, DOI={10.1088/0957-4484/19/26/265301}, abstractNote={We have designed a novel atomic layer deposition (ALD) Al2O3 spacer mask technique for fabricating large area high density nanoscale magnetic rings by photolithography for magnetic random access memory applications. A simple mask design and a low temperature ALD process were utilized to simplify the process. Dry etching of Al2O3 and cobalt was investigated for optimizing the nanostructure dimension control. A ring array with density and dimensions below the limits for photolithography tools has been achieved. The magnetic behavior of the ring array was characterized using a SQUID (superconducting quantum interference device). The switching distribution and effects of interaction among ring arrays were studied by correlating simulation with experimental results.}, number={26}, journal={NANOTECHNOLOGY}, author={Luo, Yong and Du, Yan and Misra, Veena}, year={2008}, month={Jul} }