2008 journal article

Modulation of pulmonary inflammatory responses and antimicrobial defenses in mice exposed to diesel exhaust


By: K. Gowdy n, Q. Krantz*, M. Daniels*, W. Linak*, I. Jaspers* & M. Gilmour*

author keywords: diesel exhaust; inflammation; lung; surfactant proteins; clara cell; mice
MeSH headings : Air Pollutants / toxicity; Animals; Cytokines / drug effects; Cytokines / metabolism; Female; Intercellular Adhesion Molecule-1 / drug effects; Intercellular Adhesion Molecule-1 / metabolism; Lung / drug effects; Lung / pathology; Mice; Mice, Inbred BALB C; Neutrophils / drug effects; Neutrophils / metabolism; Occupational Exposure / adverse effects; Pneumonia / chemically induced; Pulmonary Surfactant-Associated Protein A / drug effects; Pulmonary Surfactant-Associated Protein A / metabolism; Pulmonary Surfactant-Associated Protein D / drug effects; Pulmonary Surfactant-Associated Protein D / metabolism; Respiratory Tract Infections / etiology; Time Factors; Up-Regulation / drug effects; Uteroglobin / drug effects; Uteroglobin / metabolism; Vehicle Emissions / toxicity
TL;DR: Exposure to moderate and high occupational levels of DE caused an increase in lung injury and inflammation, and a decrease in host defense molecules, which could result in increased susceptibility to respiratory pathogens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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