Works (2)

Updated: August 16th, 2024 13:38

1997 journal article

A conditional sterol esterification defect in yeast having either a SEC1 or SEC5 mutation in the secretory pathway

Yeast, 13(5), 449–462.

By: M. Tomeo n, L. Palermo n, S. Tove n & L. Parks n

TL;DR: Two temperature‐conditional secretory mutations, sec1 and sec5, cause the accumulation of post‐Golgi vesicles when strains containing these mutations are grown at 37°C, and double mutants containing sec6, sec14 or sec18 with either a sec1 or sec5 mutation have normal esterification levels. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Assessment of the essentiality of ERG genes late in ergosterol biosynthesis in Saccharomyces cerevisiae

CURRENT GENETICS, 32(2), 93–99.

By: L. Palermo n, F. Leak n, S. Tove n & L. Parks n

author keywords: ergosterol; ERG genes; yeast; Saccharomyces
MeSH headings : 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases / genetics; Ergosterol / biosynthesis; Genes, Fungal; Methyltransferases / genetics; Mutation; Oxidoreductases / genetics; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / growth & development; Saccharomyces cerevisiae / metabolism; Selection, Genetic
TL;DR: A general trend was seen in which the earlier in the biosynthetic pathway that a mutation occurred, the less able the strain producing the defective sterols could compete with the ergosterol-producing strains. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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