Works (42)

2010 journal article

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor

Toxicology and Applied Pharmacology, 245(3), 335–343.

By: R. Casabar, P. Das, G. DeKrey, C. Gardiner, Y. Cao, R. Rose, A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Metabolic interactions of agrochemicals in humans

Hodgson, E., & Rose, R. L. (2008, June). PEST MANAGEMENT SCIENCE, Vol. 64, pp. 617–621.

By: E. Hodgson & R. Rose

author keywords: cytochrome P450; environmental chemicals; hepatocytes; human metabolism; organophosphorus chemicals; risk assessment
Source: Web Of Science
Added: August 6, 2018

2007 article

Human metabolic interactions of environmental chemicals

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, Vol. 21, pp. 182–186.

By: E. Hodgson & R. Rose

author keywords: carbaryl; chlorpyrifos; chlorpyrifos oxon; cytochrome P450 (CYP); DEET; Endosulfan; environmental chemicals; estradiol; fipronil; Hepatocytes; human metabolism; naphthalene; nonane; organophosphorus chemicals; permethrin; pyrethroids; testosterone
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Inhibition of fipronil and nonane metabolism in human liver microsomes and human cytochrome P450 isoforms by chlorpyrifos

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 21(2), 76–80.

By: H. Joo, K. Choi, R. Rose & E. Hodgson

author keywords: fipronil; nonane; human liver microsomes; cytochrome P450; CYP2B6; CYP3A4
Source: Web Of Science
Added: August 6, 2018

2007 review

The importance of cytochrome P4502B6 in the human metabolism of environmental chemicals

[Review of ]. PHARMACOLOGY & THERAPEUTICS, 113(2), 420–428.

By: E. Hodgson & R. Rose

author keywords: agrochemicals; cytochrome p450; cytochrome p450 2B6; environmental chemicals; induction; industrial chemicals; inhibition; metabolism; polymorphisms; xenobiotics
Source: Web Of Science
Added: August 6, 2018

2006 article

Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes

Das, P. C., Cao, Y., Cherrington, N., Hodgson, E., & Rose, R. L. (2006, December 15). CHEMICO-BIOLOGICAL INTERACTIONS, Vol. 164, pp. 200–214.

author keywords: fipronil; human hepatic and HepG2 cells; CYP3A4; CYP2B6; CYP1A1; cytotoxicity; apoptosis
Source: Web Of Science
Added: August 6, 2018

2006 article

In vitro metabolism of naphthalene by human liver microsomal cytochrome P450 enzymes

Cho, T. M., Rose, R. L., & Hodgson, E. (2006, January). DRUG METABOLISM AND DISPOSITION, Vol. 34, pp. 176–183.

By: T. Cho, R. Rose & E. Hodgson

Source: Web Of Science
Added: August 6, 2018

2006 article

Inhibition of the human liver microsomal and human cytochrome P450 1A2 and 3A4 metabolism of estradiol by deployment-related and other chemicals

Usmani, K. A., Cho, T. M., Rose, R. L., & Hodgson, E. (2006, September). DRUG METABOLISM AND DISPOSITION, Vol. 34, pp. 1606–1614.

By: K. Usmani*, T. Cho, R. Rose & E. Hodgson

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Metabolism of chlorpyrifos and chlorpyrifos oxon by human hepatocytes

Journal of Biochemical and Molecular Toxicology, 20(6), 279–291.

By: K. Choi, H. Joo, R. Rose & E. Hodgson

Source: NC State University Libraries
Added: August 6, 2018

2006 article

Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4

Casabar, R. C. T., Wallace, A. D., Hodgson, E., & Rose, R. L. (2006, October). DRUG METABOLISM AND DISPOSITION, Vol. 34, pp. 1779–1785.

By: R. Casabar n, A. Wallace, E. Hodgson & R. Rose

Source: Web Of Science
Added: August 6, 2018

2006 review

Organophosphorus chemicals: Potent inhibitors of the human metabolism of steroid hormones and xenobiotics

[Review of ]. DRUG METABOLISM REVIEWS, 38(1-2), 149–162.

By: E. Hodgson & R. Rose

author keywords: carbaryl; chlorpyrifos; chlorpyrifos oxon; cytochrome P450 (CYP); DEET; estradiol; human CYP isoforms; human liver microsomes; organophosphorus insecticides; permethrin; testosterone
Source: Web Of Science
Added: August 6, 2018

2005 review

Human metabolism and metabolic interactions of deployment-related chemicals

[Review of ]. DRUG METABOLISM REVIEWS, 37(1), 1–39.

By: E. Hodgson & R. Rose

author keywords: alcohol dehydrogenase; aldehyde dehydrogenase; carbamates; chemical warfare agents; cytochrome P450; deployment-related chemicals; jet fuel components; metabolic interactions; metabolism; organophosphorus compounds; pyrethroids; repellents; xenobiotic-metabolizing enzymes
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Pesticide metabolism and potential for metabolic interactions

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 19(4), 276–277.

By: R. Rose & E. Hodgson

Source: Web Of Science
Added: August 6, 2018

2005 journal article

Pesticide metabolism in humans, including polymorphisms

Scandinavian Journal of Work, Environment & Health, 31, 156–163.

By: R. Rose, J. Tang, J. Choi, Y. Cao, A. Usmani, N. Cherrington, E. Hodgson

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

The metabolism of nonane, a JP-8 jet fuel component, by human liver microsomes, P450 isoforms and alcohol dehydrogenase and inhibition of human P450 isoforms by JP-8

CHEMICO-BIOLOGICAL INTERACTIONS, 151(3), 203–211.

By: J. Edwards n, R. Rose & E. Hodgson

author keywords: nonane; JP-8; metabolism; cytochrome P450; alcohol dehydrogenase
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Toxicology of AHS important chemicals

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 19(3), 180–181.

By: E. Hodgson & R. Rose

Source: Web Of Science
Added: August 6, 2018

2004 journal article

In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol

CHEMICO-BIOLOGICAL INTERACTIONS, 150(3), 221–232.

By: K. Usmani n, E. Hodgson & R. Rose

author keywords: carbofuran; metabolism; human liver microsomes; cytochrome P450; CYP3MA4; testosterone; interactions
Source: Web Of Science
Added: August 6, 2018

2004 journal article

In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam

CHEMICO-BIOLOGICAL INTERACTIONS, 147(3), 319–329.

By: J. Tang, K. Usmani n, E. Hodgson & R. Rose

author keywords: fipronil; metabolism; human liver microsomes; cytochrome p450; CYP3A4; interaction
Source: Web Of Science
Added: August 6, 2018

2004 journal article

In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily

DRUG METABOLISM AND DISPOSITION, 32(3), 333–339.

By: K. Usmani n, E. Karoly, E. Hodgson & R. Rose

Source: Web Of Science
Added: August 6, 2018

2003 journal article

Inhibition and activation of the human liver microsomal and human cytochrome P450 3A4 metabolism of testosterone by deployment-related chemicals

DRUG METABOLISM AND DISPOSITION, 31(4), 384–391.

By: K. Usmani n, R. Rose & E. Hodgson

Source: Web Of Science
Added: August 6, 2018

2002 journal article

In vitro human metabolism and interactions of repellent N,N-diethyl-M-toluamide

DRUG METABOLISM AND DISPOSITION, 30(3), 289–294.

By: K. Usmani n, R. Rose, J. Goldstein, W. Taylor, A. Brimfield & E. Hodgson

Source: Web Of Science
Added: August 6, 2018

2002 journal article

In vitro human metabolism of permethrin: the role of human alcohol and aldehyde dehydrogenases

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 74(3), 117–128.

By: J. Choi, R. Rose & E. Hodgson

author keywords: permethrin; permethrin metabolism; human alcohol dehydrogenase; human aldehyde dehydrogenase
Source: Web Of Science
Added: August 6, 2018

2002 journal article

In vitro metabolism of carbaryl by human cytochrome P450 and its inhibition by chlorpyrifos

CHEMICO-BIOLOGICAL INTERACTIONS, 141(3), 229–241.

By: J. Tang, Y. Cao, R. Rose & E. Hodgson

author keywords: carbaryl; human lifer microsomes; metabolism
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Cloning, sequencing, heterologous expression, and ch;characterization of murine cytochrome p450 3a25*(Cyp3a25), a testosterone 6 beta-hydroxylase

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 15(2), 90–99.

By: D. Dai*, R. Bai n, E. Hodgson & R. Rose

author keywords: Cyp3a-25; cloning; sequencing; heterologous expression; metabolism and distribution; testosterone 6 beta-hydroxylase
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Identification of variants of CYP3A4 and characterization of their abilities to metabolize testosterone and chlorpyrifos

Journal of Pharmacology and Experimental Therapeutics, 299(3), 825–831.

By: D. Dai, J. Tang, R. Rose, E. Hodgson, R. Bienstock, H. Mohrenweiser, J. Goldstein

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Metabolism of chlorpyrifos by human cytochrome P450 isoforms and human, mouse, and rat liver microsomes

Drug Metabolism and Disposition, 29(9), 1201–1204.

By: J. Tang, Y. Cao, R. Rose, A. Brimfield, D. Dai, J. Goldstein, E. Hodgson

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene, vinclozolin, and flutamide

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 70(3), 127–141.

By: D. Dai*, Y. Cao, G. Falls*, P. Levi, E. Hodgson & R. Rose

Source: Web Of Science
Added: August 6, 2018

2001 journal article

Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 15(6), 300–308.

By: E. Karoly & R. Rose

author keywords: FMO2; sequence; characterization; expression; mouse
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Comparative metabolism of chloroacetamide herbicides and selected metabolites in human and rat liver microsomes.

ENVIRONMENTAL HEALTH PERSPECTIVES, 108(12), 1151–1157.

author keywords: chloroacetamide herbicides; human cytochrome P450; in vitro metabolism
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Detection of resistant insects and IPM

Emerging Technologies for Integrated Pest Management : Concepts, Research, and Implementation, 67.

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Flavin-containing monooxygenase isoform specificity for the N-oxidation of tamoxifen determined by product measurement and NADPH oxidation

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 14(2), 118–120.

By: E. Hodgson, R. Rose, Y. Cao, S. Dehal* & D. Kupfer*

author keywords: flavin-containing monooxygenase; FMO; FMO isoforms; tamoxifen; human; mouse
Source: Web Of Science
Added: August 6, 2018

1999 article

In vitro metabolism of alachlor by human liver microsomes and human cytochrome P450 isoforms

Coleman, S., Liu, S. M., Linderman, R., Hodgson, E., & Rose, R. L. (1999, August 30). CHEMICO-BIOLOGICAL INTERACTIONS, Vol. 122, pp. 27–39.

author keywords: alachlor; CDEPA; human CYP; herbicides
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Metabolism of [C-14]prometryn in rats

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 47(9), 3858–3865.

By: M. Maynard*, D. Brumback, W. Itterly, T. Capps & R. Rose

author keywords: prometryn; metabolites; rats; in vivo; in vitro; cytochrome P-450; FMO
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Basic principles and rationale for the use of insect genes in bioremediation: esterases, phosphotriesterase, cytochrome P450 and epoxide hydrolase

Reviews in Toxicology, 2(1998), 169–178.

By: R. Roe, E. Hodgson, R. Rose, D. Thompson, C. Devorshak, D. Anspaugh, R. Linderman, S. Harris, M. Tomalski

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Flavin-containing monooxygenase and cytochrome P450 mediated metabolism of pesticides: from mouse to human

Reviews in Toxicology, 2(1998), 231–243.

By: E. Hodgson, N. Cherrington, S. Coleman, S. Liu, J. Falls, Y. Cao, J. Goldstein, R. Rose

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Molecular cloning, sequence, and expression of mouse flavin-containing monooxygenases 1 and 5 (FMO1 and FMO5)

Journal of Biochemical and Molecular Toxicology, 12(1998), 205–212.

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5

XENOBIOTICA, 28(7), 673–682.

Source: Web Of Science
Added: August 6, 2018

1997 journal article

Cytochrome P450 (CYP)9A1 in Heliothis virescens: The first member of a new CYP family

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 27(6), 605–615.

By: R. Rose, D. Goh, D. Thompson, K. Verma, D. Heckel*, L. Gahan*, R. Roe, E. Hodgson

author keywords: CYP9A1; cytochrome P450; insecticide resistance; Heliothis virescens
Sources: Web Of Science, ORCID
Added: August 6, 2018

1997 journal article

Molecular cloning, sequencing, and expression in Escherichia coli of mouse flavin-containing monooxygenase 3 (FMO3): Comparison with the human isoform

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 347(1), 9–18.

By: J. Falls, N. Cherrington, K. Clements, R. Philpot*, P. Levi n, R. Rose, E. Hodgson

author keywords: flavin-containing monooxygenase 3; FMO3; FMO3 sequence; FMO3 expression
Source: Web Of Science
Added: August 6, 2018

1996 patent

Insecticide resistance associated cytochrome 450

Washington, DC: U.S. Patent and Trademark Office.

By: R. Roe, E. Hodgson & R. Rose

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

CYTOCHROME P450-ASSOCIATED INSECTICIDE RESISTANCE AND THE DEVELOPMENT OF BIOCHEMICAL DIAGNOSTIC ASSAYS IN HELIOTHIS-VIRESCENS

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 51(3), 178–191.

By: R. Rose, L. Barbhaiya n, R. Roe n, G. Rock n & E. Hodgson n

Source: Web Of Science
Added: August 6, 2018

1991 journal article

DIFFERENCES IN CYTOCHROME-P450 ACTIVITIES IN TOBACCO BUDWORM LARVAE AS INFLUENCED BY RESISTANCE TO HOST PLANT ALLELOCHEMICALS AND INDUCTION

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 99(3), 535–540.

By: R. Rose, F. Gould n, P. Levi n & E. Hodgson n

Source: Web Of Science
Added: August 6, 2018