@article{shinozaki_sellon_cantor_besser_mealey_vaden_2002, title={Fecal polymerase chain reaction with 16S ribosomal RNA primers can detect the presence of gastrointestinal Helicobacter in dogs}, volume={16}, ISSN={["0891-6640"]}, DOI={10.1892/0891-6640(2002)016<0426:FPCRWR>2.3.CO;2}, abstractNote={Questions about pathogenesis and therapy for Helicobacter infections in dogs could be answered with a simple, noninvasive, sensitive, and specific diagnostic test. We hypothesized that a fecal polymerase chain reaction (PCR) assay would detect Helicobacter and could be useful for assessing therapeutic responses. Paired gastric biopsies and fecal samples were obtained from 39 random source dogs (group 1). Gastric biopsies from each of these dogs had histologic evidence of gastric spiral bacteria, and paired gastric tissue and fecal samples produced a 375-base pair (bp) product when amplified by PCR with Helicobacter-specific primers. Specificity of the PCR product was confirmed by detection of expected 60-, 119-, and 196-bp products following Hinfl digestion. Direct sequencing of amplicons from paired PCR products from gastric biopsy and fecal samples from 8 group I dogs showed that gastric products had the highest homologies with known gastric Helicobacter species, whereas fecal products had the highest homologies with intestinal species. Healthy mixed-breed dogs (group II; n = 8) with histologically confirmed spiral bacteria infection were treated with a 21-day course of metronidazole, amoxicillin, and famotidine. Fecal samples were collected from group II dogs twice before and within 3 days of completion of treatment. The PCR results correctly identified 15/16 pretreatment samples as positive: 1 pretreatment sample was negative. PCR results identified 8/8 posttreatment samples as Helicobacter negative. Fecal PCR is a useful test for detecting Helicobacter infection in dogs. This assay may be useful as a screening test for infection and could be used to address questions relevant to pathogenesis and therapy.}, number={4}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Shinozaki, JK and Sellon, RK and Cantor, GH and Besser, TE and Mealey, KL and Vaden, SL}, year={2002}, pages={426–432} }
 @article{savary_sellon_law_2001, title={Chylous abdominal effusion in a cat with feline infectious peritonitis}, volume={37}, ISSN={["0587-2871"]}, DOI={10.5326/15473317-37-1-35}, abstractNote={A 10-year-old cat was diagnosed with chyloperitoneum based on the effusion characteristics. Feline coronavirus serology was positive. The owner declined further evaluation and elected euthanasia. Necropsy revealed vasculitis with multifocal areas of necrosis and lymphocytic-plasmacytic inflammation in multiple solid organs, most likely due to feline infectious peritonitis (FIP). Immunohistochemistry was negative for FIP antigen. Notwithstanding, the final diagnosis of FIP was based on the characteristic histopathological lesions. Underlying causes of chyloperitoneum in cats and humans are discussed, and possible pathogenesis of the chyloperitoneum in association with a vasculitis such as FIP is discussed.}, number={1}, journal={JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION}, author={Savary, KCM and Sellon, RK and Law, JM}, year={2001}, pages={35–40} }
 @article{vaden_sellon_melgarejo_williams_trogdon_vancamp_argenzio_2000, title={Evaluation of intestinal permeability and gluten sensitivity in Soft-Coated Wheaten Terriers with familial protein-losing enteropathy, protein-losing nephropathy, or both}, volume={61}, ISSN={["0002-9645"]}, DOI={10.2460/ajvr.2000.61.518}, abstractNote={Abstract}, number={5}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Vaden, SL and Sellon, RK and Melgarejo, LT and Williams, DA and Trogdon, MM and VanCamp, SD and Argenzio, RA}, year={2000}, month={May}, pages={518–524} }
 @article{dieleman_arends_tonkonogy_goerres_craft_grenther_sellon_balish_sartor_2000, title={Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10-deficient mice}, volume={68}, ISSN={["1098-5522"]}, DOI={10.1128/IAI.68.9.5107-5113.2000}, abstractNote={ABSTRACT}, number={9}, journal={INFECTION AND IMMUNITY}, author={Dieleman, LA and Arends, A and Tonkonogy, SL and Goerres, MS and Craft, DW and Grenther, W and Sellon, RK and Balish, E and Sartor, RB}, year={2000}, month={Sep}, pages={5107–5113} }
 @article{morteau_morham_sellon_dieleman_langenbach_smithies_sartor_2000, title={Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2}, volume={105}, ISSN={["1558-8238"]}, DOI={10.1172/JCI6899}, abstractNote={To investigate roles in intestinal inflammation for the 2 cyclooxygenase (COX) isoforms, we determined susceptibility to spontaneous and induced acute colitis in mice lacking either the COX-1 or COX-2 isoform. We treated wild-type, COX-1(-/-), COX-2(-/-), and heterozygous mice with dextran sodium sulfate (DSS) to provoke acute colonic inflammation, and we quantified tissue damage, prostaglandin (PG) E(2), and interleukin-1beta. No spontaneous gastrointestinal inflammation was detected in mice homozygous for either mutation, despite almost undetectable basal intestinal PGE(2) production in COX-1(-/-) mice. Both COX-1(-/-) and COX-2(-/-) mice showed increased susceptibility to a low-dose of DSS that caused mild colonic epithelial injury in wild-type mice. COX-2(-/-) mice were more susceptible than COX-1(-/-) mice, and selective pharmacologic blockade of COX-2 potentiated injury in COX-1(-/-) mice. At a high dose, DSS treatment was fatal to 50% of the animals in each mutant group, but all wild-type mice survived. DSS treatment increased PGE(2) intestinal secretion in all groups except COX-2(-/-) mice. These results demonstrate that COX-1 and COX-2 share a crucial role in the defense of the intestinal mucosa (with inducible COX-2 being perhaps more active during inflammation) and that neither isoform is essential in maintaining mucosal homeostasis in the absence of injurious stimuli.}, number={4}, journal={JOURNAL OF CLINICAL INVESTIGATION}, author={Morteau, O and Morham, SG and Sellon, R and Dieleman, LA and Langenbach, R and Smithies, O and Sartor, RB}, year={2000}, month={Feb}, pages={469–478} }
 @article{schultz_tonkonogy_sellon_veltkamp_godfrey_kwon_grenther_balish_horak_sartor_1999, title={IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation}, volume={276}, ISSN={["1522-1547"]}, DOI={10.1152/ajpgi.1999.276.6.g1461}, abstractNote={Interleukin-2 (IL-2) amplifies immune stimuli and influences B cell differentiation. IL-2-deficient mice spontaneously develop intestinal inflammation if raised under specific pathogen-free (SPF) conditions. We quantitatively determined the aggressiveness and kinetics of gastrointestinal and hepatic inflammation in the presence or absence of viable bacteria in IL-2-deficient mice. Breeding colonies were maintained under SPF and germfree (GF) conditions. Intestinal tissues, serum, and mesenteric lymph nodes were obtained from mice at different ages for blind histological scoring, immunoglobulin measurements, mucosal T cell infiltration, and cytokine secretion. GF IL-2 −/− mice developed mild, focal, and nonlethal intestinal inflammation with delayed onset, whereas the more aggressive inflammation in SPF IL-2 −/− mice led to their death between 28 and 32 wk. Periportal hepatic inflammation was equal in the presence or absence of bacterial colonization. Intestinal immunoglobulin secretion decreased significantly by 13 wk of age in IL-2 −/− mice in both GF and SPF environments. In contrast to other genetically engineered rodents, IL-2 −/− mice develop mild focal gastrointestinal and active portal tract inflammation in the absence of viable bacteria.}, number={6}, journal={AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY}, author={Schultz, M and Tonkonogy, SL and Sellon, RK and Veltkamp, C and Godfrey, VL and Kwon, J and Grenther, WB and Balish, E and Horak, I and Sartor, RB}, year={1999}, month={Jun}, pages={G1461–G1472} }
 @article{johnson_papadi_tompkins_sellon_orandle_bellah_bubenik_1998, title={Biphasic thymus response by kittens inoculated with feline immunodeficiency virus during fetal development}, volume={35}, ISSN={["0300-9858"]}, DOI={10.1177/030098589803500304}, abstractNote={The objective of this study was to assess the response of the feline thymus to fetal infection with feline immunodeficiency virus (FIV), an animal model for human immunodeficiency virus infection. Thirteen feline embryos from four litters were directly inoculated with FIV during the sixth week postbreeding, a period corresponding to the late second trimester of pregnancy. Thymus tissue was collected and analyzed from randomly selected kittens at 2, 4, and 16 weeks postinoculation (PI) and compared to age-matched control kittens that did not receive fetal inoculations. Of three kittens evaluated at 2 weeks PI (week 8 of gestation), neither thymus: body weight ratio nor histologic structure differed from five age-matched control animals. However, analysis of thymocyte subpopulations by flow cytometry revealed a significant ( P = 0.011) reduction in the percentage of cluster of differentiation (CD)4+/CD8+cells from an average of 66% in control fetuses to 45% in infected fetuses. FIV RNA transcription, assessed by in situ hybridization using an FIV gag RNA probe, was widely distributed throughout the thymus in patterns suggestive of both stromal and parenchymal infection. By 4 weeks PI (week 1 postpartum), the thymus: body weight ratio was significantly reduced ( P = 0.007) from 0.36% in five control kittens to 0.13% in four fetal inoculates. Severely atrophied thymus lobules supported minimal virus transcription and mean CD4+/CD8+thymocyte percentages were lower ( P = 0.021) in infected kittens (15%) compared to age-matched controls (66%). By 16 weeks PI (week 12 postpartum), thymus:body weight ratios of six inoculated kittens were not significantly different from six age-matched controls, suggesting that partial postnatal thymus regeneration had occurred. However, despite similar size, the regenerative thymus contained reduced percentages of CD4+/CD8+thymocytes (infected: 40% versus control: 76%; P = 0.009) and increased percentages of CD4+/CD8-(11% versus 5%; P = 0.002) and CD4-/CD8+(16% versus 9%; P = 0.035) lymphocytes. These changes were associated with widespread FIV transcription within thymic lymphocytes. Thus, the thymus of kittens infected with FIV during late fetal development is characterized by two distinct changes: neonatal atrophy and postnatal regeneration. Despite a recovery in thymus weight, thymus regeneration ineffectively restores the normal phenotypic distribution of thymocytes and supports FIV transcription.}, number={3}, journal={VETERINARY PATHOLOGY}, author={Johnson, CM and Papadi, GP and Tompkins, WA and Sellon, RK and Orandle, MS and Bellah, JR and Bubenik, LJ}, year={1998}, month={May}, pages={191–201} }
 @article{spann_sellon_thrall_bostian_boston_1998, title={Computed tomographic diagnosis: Use of computed tomography to distinguish a pulmonary mass from alveolar disease}, volume={39}, ISSN={["1058-8183"]}, DOI={10.1111/j.1740-8261.1998.tb01645.x}, abstractNote={Veterinary Radiology & UltrasoundVolume 39, Issue 6 p. 532-535 COMPUTED TOMOGRAPHIC DIAGNOSIS: USE OF COMPUTED TOMOGRAPHY TO DISTINGUISH A PULMONARY MASS FROM ALVEOLAR DISEASE Dennis R. Spann DVM, Corresponding Author Dennis R. Spann DVM Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Address correspondence and reprint requests to Dennis R. Spann, DVM, Veterinary Medical Teaching Hospital Department of Small Animal Medicine, University of California-Davis, Davis, CA 95616.Search for more papers by this authorRance K. Sellon DVM PHD, Rance K. Sellon DVM PHD Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorDonald E. Thrall DVM, PHD, Donald E. Thrall DVM, PHD Department of Anatomy, Physiological Sciences, and Radiology, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorAudrey E. Bostian DVM, Audrey E. Bostian DVM Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorGary T. Boston DVM, Gary T. Boston DVM Department of Microbiology, Pathology, and Parasitology, Countryside Pet Hospital, 508-S 10th Street NW, Conover, NC 28613Search for more papers by this author Dennis R. Spann DVM, Corresponding Author Dennis R. Spann DVM Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Address correspondence and reprint requests to Dennis R. Spann, DVM, Veterinary Medical Teaching Hospital Department of Small Animal Medicine, University of California-Davis, Davis, CA 95616.Search for more papers by this authorRance K. Sellon DVM PHD, Rance K. Sellon DVM PHD Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorDonald E. Thrall DVM, PHD, Donald E. Thrall DVM, PHD Department of Anatomy, Physiological Sciences, and Radiology, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorAudrey E. Bostian DVM, Audrey E. Bostian DVM Department of Companion Animal and Special Species, North Carolina State University, College of Veterinary Medicine, 4700 Hillsborough Street, Raleigh, NC 27606Search for more papers by this authorGary T. Boston DVM, Gary T. Boston DVM Department of Microbiology, Pathology, and Parasitology, Countryside Pet Hospital, 508-S 10th Street NW, Conover, NC 28613Search for more papers by this author First published: 23 May 2005 https://doi.org/10.1111/j.1740-8261.1998.tb01645.xCitations: 15AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCE 1 Suter PF, Carrig C, O'Brien TR, Koller D. Radiographic recognition of primary and metastatic pulmonary neoplasia of dogs and cats. J Am Vet Radiol Soc 1974; 15: 3–24. 2 Lamb CR. The canine lung. In: DE Thrall. Textbook of veterinary diagnostic radiology, 2nd ed. Philadelphia : WB Saunders, 1994: 331–346. 3 Tidwell AS. Diagnostic pulmonary imaging. Problems Vet Med 1992; 4: 239–264. 4 Postorino NC, Wheeler SL, Park RD, et al. A syndrome resembling lymphomatoid granulomatosis in a dog. J Vet Int Med 1989; 3: 15–19. 5 Berry CR, Moore PF, Thomas WP, et al. Pulmonary lymphomatoic granulomatosis in seven dogs (1976–1987). J Vet Int Med 1990; 4: 157–166. 6 Calvert CA, Mahaffey MB, Lappin MR, Farrell RL. Pulmonary and disseminated eosinophilic granulomatosis in a dog. J Am Anim Hosp Assoc 1988; 24: 311–319. 7 Walker MA. Thoracic blastomycosis: A review of its radiographic manifestation in 40 dogs. Vet Radiol 1981; 22: 22–26. 8 Hawkins EC. Transtracheal wash and bronchoalveolar lavage in the management of respiratory disease. In: RW Kirk, JD Bonagura. Current veterinary therapy XI: Small animal practice. Philadelphia , WB Saunders Co, 1992: 795–800. 9 Hawkins EC, De Nicola DB, Plier ML. Cytologic analysis of bronchoalveolar lavage fluid in the diagnosis of spontaneous respiratory tract disease in dogs: A retrospective study. J Vet Intern Med 1995; 9: 386–392. 10 Teske E, Stokhof AA, van der Ingh TSGAM, et al. Transthoracic needle aspiration biopsy of the lung in dogs with pulmonic disease. J Am Anim Hosp Assoc 1991; 27: 289–294. 11 Turrel JM, Fike JR, LeCouter RA, Higgins RJ. Computed tomographic characteristics of primary brain tumors in 50 dogs. JAVMA 1986; 188: 851–856. 12 LeCouter RA, Fike JR, Scagliotti RH, Cann CE. Computed tomography of orbital tumors in the dog. JAVMA 1982; 180: 910–913. 13 Burk RL. Computed tomographic imaging of nasal disease in 100 dogs. Vet Radiol & Ultrasound 1992; 33: 170–176. 14 Drost WT, Love NE, Berry CR. Comparison of radiography, myelography, and computed tomography for the evaluation of canine vertebral and spinal cord tumors in sixteen dogs. Vet Radiol & Ultrasound 1996; 37: 28–33. 15 Jones JC, Sorjonen DC, Simpson ST, et al. Comparison between computed tomographic and surgical findings in nine large-breed dogs with lumbosacral stenosis. Vet Radiol & Ultrasound 1996; 37: 247–256. 16 Bailey MQ. Use of x-ray computed tomography as an aid in localization of adrenal masses in the dog. JAVMA 1986; 188: 1046–1049. 17 Smallwood JE, George TF. Anatomic atlas for computed tomography in the mesaticephalic dog: Thorax and cranial abdomen. Vet Radiol & Ultrasound 1993; 34: 65–84. 18 Chen QC, Klein JS, Gamsu G, Webb WR. High-resolution computed tomography of the mammalian lung. Am J Vet Res 1992; 53: 1218–1224. 19 Burk RL. Computed tomography of thoracic diseases in dogs. JAVMA 1991; 199: 617–621. Citing Literature Volume39, Issue6November 1998Pages 532-535 ReferencesRelatedInformation}, number={6}, journal={VETERINARY RADIOLOGY & ULTRASOUND}, author={Spann, DR and Sellon, RK and Thrall, DE and Bostian, AE and Boston, GT}, year={1998}, pages={532–535} }
 @article{sellon_tonkonogy_schultz_dieleman_grenther_balish_rennick_sartor_1998, title={Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation ininterleukin-10-deficient mice}, volume={66}, number={11}, journal={Infection and Immunity}, author={Sellon, R. K. and Tonkonogy, S. and Schultz, M. and Dieleman, L. A. and Grenther, W. and Balish, E. and Rennick, D. M. and Sartor, R. B.}, year={1998}, pages={5224–5231} }
 @article{gookin_sellon_mcdorman_geoly_1998, title={Systemic Plasmacytosis and Polyclonal Gammopathy in a Dog}, volume={12}, ISSN={0891-6640 1939-1676}, url={http://dx.doi.org/10.1111/j.1939-1676.1998.tb02152.x}, DOI={10.1111/j.1939-1676.1998.tb02152.x}, abstractNote={Journal of Veterinary Internal MedicineVolume 12, Issue 6 p. 471-474 Open Access Systemic Plasmacytosis and Polyclonal Gammopathy in a Dog Jody L. Gookin, Jody L. Gookin Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this authorRanee K. Sellon, Corresponding Author Ranee K. Sellon Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh, NC Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164–6610; e-mail: [email protected]Search for more papers by this authorKevin S. McDorman, Kevin S. McDorman Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this authorFrank J. Geoly, Frank J. Geoly Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this author Jody L. Gookin, Jody L. Gookin Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this authorRanee K. Sellon, Corresponding Author Ranee K. Sellon Department of Companion Animal and Special Species Medicine, College of Veterinary Medicine, North Carolina State University, Raleigh, NC Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA 99164–6610; e-mail: [email protected]Search for more papers by this authorKevin S. McDorman, Kevin S. McDorman Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this authorFrank J. Geoly, Frank J. Geoly Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, NCSearch for more papers by this author First published: 05 February 2008 https://doi.org/10.1111/j.1939-1676.1998.tb02152.xCitations: 1 Dr. Sellon is presently affiliated with the Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Edgell CJS. McDonald CC, Graham IB. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc Natl Acad Sci USA 1983; 80: 3734– 3737. 2 Rivas AI, Tintle L., Kimball ES, et al. A canine febrile disorder associated with elevated interleukin-6. Clin Immunol Immunopathol 1992; 64: 36– 45. 3 Watanabe S., Ohara K., Kukita A., et al. Systemic plasmacytosis: A syndrome of peculiar multiple skin eruptions, generalized lymphadenopathy, and polyclonal hypergammaglobulinemia. Arch Dermatol 1986; 122: 1314– 1320. 4 Uhara H., Saida T., Ikegawa S., et al. Primary cutaneous plasmacytosis: Report of three cases and review of the literature. Dermatology 1994; 189: 251– 255. 5 Kodama A., Tani M., Hori K., et al. Systemic and cutaneous plasmacytosis with multiple skin lesions and polyclonal hypergammaglobulinemia: Significant serum interleukin-6 levels. Br J Dermatol 1992; 127: 49– 53. 6 Lee DW, Choi SW, Park JW, et al. Systemic plasmacytosis: A case which improved with melphalan. J Dermatol 1995; 22: 205– 209. 7 Ishii N., Hayashi M., Nakajima H., et al. A case of cutaneous plasmacytosis. J Dermatol 1984; 11: 565– 569. 8 Aso M., Shimao S. An unusual case of cutaneous plasmacytosis. J Dermatol 1982; 9: 149– 152. 9 Kitamura K., Tamura N., Hatano H., et al. A case of plasmacytosis with multiple peculiar eruptions. J Dermatol 1980; 7: 341– 349. 10 Ogilvie GK, Moore AS. Managing the Veterinary Cancer Patient. Trenton , NJ : Veterinary Learning Systems; 1995: 280– 290. 11 Vail DM. Plasma cell neoplasms. In: SJ Withrow, EG MacEwen, eds. Small Animal Clinical Oncology. Philadelphia , PA : WB Saunders; 1996: 509– 520. 12 Matus RE, Leifer CE, MacEwen EG, et al. Prognostic factors for multiple myeloma in the dog. J Am Vet Med Assoc 1986; 188: 1288– 1292. 13 Scott DW, Miller WH, Griffin CG. Small Animal Dermatology. Philadelphia , PA : WB Saunders; 1995: 1073– 1076. 14 Clark GN, Berg J., Engler SJ, et al. Extramedullary plasmacytomas in dogs: Results of surgical excision in 131 cases. J Am Anim Hosp Assoc 1992; 28: 105– 111. 15 Walton GS, Gopinath C. Multiple myeloma in a dog with some unusual features. J Small Anim Pract 1972; 13: 703– 708. 16 Trigo FJ, Hargis AM. Canine cutaneous plasmacytoma with regional lymph node metastasis. Vet Med Small Anim Clin 1983; 78: 1749– 1751. 17 Lester SJ, Mesfin GM. A solitary plasmacytoma in a dog with progression to a disseminated myeloma. Can Vet J 1980; 21: 284– 286. 18 Yager JA, Wilcock BR. Surgical Pathology of the Dog and Cat. London : Wolfe; 1994: 283– 284. 19 Kyriazidou A., Brown PJ, Lucke VM. An immunohistochemical study of canine extramedullary plasma cell tumors. J Comp Pathol 1989; 100: 256– 266. 20 DiBartola SP. Hypoglycemia and polyclonal gammopathy in a dog with plasma cell dyscrasia. J Am Vet Med Assoc 1982; 180: 1345– 1349. 21 Jain NC. Schalm's Veterinary Hematology. Philadelphia . PA : Lea & Febiger; 1986: 940– 989. 22 Larsen AE, Carpenter JL. Hepatic plasmacytoma and biclonal gammopathy in a cat. J Am Vet Med Assoc 1994; 205: 708– 710. 23 Peterson EN, Meininger AC. Immunoglobulin A and immunoglobulin G biclonal gammopathy in a dog with multiple myeloma. J Am Anim Hosp Assoc 1997; 33: 45– 47. 24 Hirano T., Suematsu S., Matsusaka T., et al. The role of interleukin 6 in plasmacytomagenesis. Ciba Foundation Symposium, 167, Polyfunctional cytokines: IL-6 and LIE 1992: 188– 200. 25 Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin Immunol Immunopathol 1992; 62: S60– S65. 26 Yoshizaki K., Kuritani T., Kishimoto T. Interleukin-6 in autoimmune disorders. Semin Immunol 1992; 4: 155– 166. 27 Suematsu S., Matsuda T., Aozasa K., et al. IgGl plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci USA 1989; 86: 7547– 7551. Citing Literature Volume12, Issue6November 1998Pages 471-474 ReferencesRelatedInformation}, number={6}, journal={Journal of Veterinary Internal Medicine}, publisher={Wiley}, author={Gookin, Jody L. and Sellon, Ranee K. and McDorman, Kevin S. and Geoly, Frank J.}, year={1998}, month={Nov}, pages={471–474} }
 @article{hess_sellon_1997, title={Steroid-responsive, cervical, pyogranulomatous pachymeningitis in a dog}, volume={33}, ISSN={["1547-3317"]}, DOI={10.5326/15473317-33-5-461}, abstractNote={Syndromes of steroid-responsive meningitis have been described in the dog and typically are characterized by neutrophilic pleocytosis and an elevated protein concentration of the cerebrospinal fluid. In a minority of cases, histopathology has demonstrated suppurative leptomeningeal (i.e., arachnoid and pia) inflammation. A case of compressive, cervical, pyogranulomatous inflammation of undetermined cause affecting the dura mater (i.e., pachymeningitis), accompanied by fever and hyperpathia, is presented. The pachymeningitis ultimately regressed with long-term immunosuppressive therapy. This case shares features with hypertrophic spinal pachymeningitis of humans, an uncommon, frequently idiopathic, chronic inflammatory disorder causing dural hypertrophy, radiculopathy, and spinal cord compression.}, number={5}, journal={JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION}, author={Hess, PR and Sellon, RK}, year={1997}, pages={461–468} }
 @article{frank_nutter_kyles_atkins_sellon_1997, title={Systemic arterial dirofilariasis in five dogs}, volume={11}, ISSN={["0891-6640"]}, DOI={10.1111/j.1939-1676.1997.tb00089.x}, abstractNote={Systemic arterial dirofilariasis is an unusual manifestation of heartworm disease of dogs that results from aberrant migration ofDirofilaria immitisinto the peripheral arterial circulation. To expand the clinical characterization of systemic arterial dirofilariasis, 5 dogs evaluated at the North Carolina State University's College of Veterinary Medicine were reviewed. Common clinical presentations included hindlimb lameness, paresthesia of hindlimbs, and interdigital ischemic necrosis resulting from thromboembolic disease. Visualization of heartworms with angiography or ultrasonography confirmed the diagnosis in all cases. All 5 dogs were treated with an adulticide; 3 dogs were treated with thiacetarsamide sodium and 2 with melarsomine dihydrochloride. Four of the 5 dogs survived the initial treatment period; 1 dog died of severe thromboembolic complications after thiacetarsamide sodium therapy. The treatment of systemic arterial dirofilariasis creates a therapeutic challenge because of multiple potential complications resulting from thromboembolic disease.}, number={3}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Frank, JR and Nutter, FB and Kyles, AE and Atkins, CE and Sellon, RK}, year={1997}, pages={189–194} }
 @article{sellon_levy_jordan_gebhard_tompkins_tompkins_1996, title={Changes in lymphocyte subsets with age in perinatal cats: Late gestation through eight weeks}, volume={53}, ISSN={["0165-2427"]}, DOI={10.1016/0165-2427(96)05556-0}, abstractNote={The age-related changes in numbers and proportions of peripheral blood lymphocyte subsets (pan-T, CD4, CD8, Ig, and null) were evaluated by two-color flow cytometry in 16 feline fetuses (56–58 days gestational age) and 21 kittens from birth through 8 weeks of age. Populations of pan-T+, CD4+, and CD8+ cells increased in total numbers as a function of increases in total lymphocyte numbers while proportions of these subsets remained relatively static. In contrast, both the total number and proportion of Ig+ cells increased from birth to 4 weeks of age, after which there were essentially no changes. Null (pan-T−), Ig− cells were highest during late gestation and declined steadily thereafter to become a minimal component of the peripheral lymphocyte subsets. Compared with normal adult values, CD4CD8 ratios were high throughout the 8 week study period. These results illustrate that the neonatal cat blood lymphocyte profile undergoes maturational changes and emphasize the importance of evaluating age-matched controls in studies of conditions that may alter feline lymphocyte subsets.}, number={1-2}, journal={VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY}, author={Sellon, RK and Levy, JK and Jordan, HL and Gebhard, DH and Tompkins, MB and Tompkins, WA}, year={1996}, month={Sep}, pages={105–113} }
 @article{sellon_bissonnette_bunch_1996, title={Long-term survival after total gastrectomy for gastric adenocarcinoma in a dog}, volume={10}, ISSN={["1939-1676"]}, DOI={10.1111/j.1939-1676.1996.tb02073.x}, abstractNote={Journal of Veterinary Internal MedicineVolume 10, Issue 5 p. 333-335 Open Access Long-Term Survival After Total Gastrectomy for Gastric Adenocarcinoma in a Dog Rance K. Sellon, Rance K. Sellon Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCSearch for more papers by this authorKevin Bissonnette, Kevin Bissonnette Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCSearch for more papers by this authorSusan E. Bunch, Corresponding Author Susan E. Bunch Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCDVM, PhD, Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough St, Raleigh, NC 27606Search for more papers by this author Rance K. Sellon, Rance K. Sellon Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCSearch for more papers by this authorKevin Bissonnette, Kevin Bissonnette Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCSearch for more papers by this authorSusan E. Bunch, Corresponding Author Susan E. Bunch Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, Raleigh, NCDVM, PhD, Department of Companion Animal and Special Species Medicine, North Carolina State University College of Veterinary Medicine, 4700 Hillsborough St, Raleigh, NC 27606Search for more papers by this author First published: September 1996 https://doi.org/10.1111/j.1939-1676.1996.tb02073.xCitations: 16AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 JL Sawyers, HW. Scott Postgastrectomy sequelae and remedial operations. In: HW Scott, JL Sawyers, eds. Surgery of the Stomach, Duodenum and Small Intestine. Boston , MA : Blackwell Scientific; 1987: 767– 776. 2 Li Destri G., Trombatore G., La Greca G., et al. Total gastrectomy: Nutritional status after different reconstruction techniques. An experimental study. J Surg Oncol 1992; 49: 98– 102. 3 Batt RM, Horadagoda NU. Role of gastric and pancreatic intrinsic factors in the physiology and absorption of cobalamin in the dog. Gastroenterology 1986; 94: A1339 (abstr). 4 Willard MD, Simpson RB, Fossum TW, et al. Characterization of naturally developing small intestinal bacterial overgrowth in 16 German Shepherd Dogs. J Am Vet Med Assoc 1994; 204: 1201– 1206. 5 Matthiesen DT. Partial gastrectomy as treatment of gastric volvulus: Results in 30 dogs. Vet Surg 1985; 14: 185– 193. Citing Literature Volume10, Issue5September 1996Pages 333-335 ReferencesRelatedInformation}, number={5}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Sellon, RK and Bissonnette, K and Bunch, SE}, year={1996}, pages={333–335} }
 @article{sellon_1996, title={Molecular pathogenesis of feline immunodeficiency virus}, volume={4}, number={3}, journal={Journal of Veterinary Allergy and Clinical Immunology}, author={Sellon, R. K.}, year={1996}, pages={87} }
 @article{sellon_jordan_kennedy-stoskopf_tompkins_tompkins_1994, title={Feline immunodeficiency virus can be experimentally transmitted via milk during acute maternal infection}, volume={68}, number={5}, journal={Journal of Virology}, author={Sellon, R. K. and Jordan, H. L. and Kennedy-Stoskopf, S. and Tompkins, M. B. and Tompkins, W. A. F.}, year={1994}, pages={3380} }
 @article{sellon_menard_meuten_lengerich_steurer_breitschwerdt_1993, title={Endemic Visceral Leishmaniasis in a Dog from Texas}, volume={7}, ISSN={0891-6640 1939-1676}, url={http://dx.doi.org/10.1111/j.1939-1676.1993.tb03163.x}, DOI={10.1111/j.1939-1676.1993.tb03163.x}, abstractNote={Visceral leishmaniasis was diagnosed by cytology and positive indirect immunofluorescent antibody titers to Leishmania donovani in a 7‐month‐old female Basenji dog from Texas. Clinical and laboratory findings included weight loss, hematochezia, hyperglobulinemia, hypoalbuminemia, anemia, and neutrophilic leukocytosis. Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. Several foci of endemic leishmaniasis have been reported in the United States. Because of its zoonotic potential and the lack of approved treatments for dogs with leishmaniasis in the United States, the development of effective treatment strategies is needed.}, number={1}, journal={Journal of Veterinary Internal Medicine}, publisher={Wiley}, author={Sellon, Rance K. and Menard, Monica M. and Meuten, Donald J. and Lengerich, Eugene J. and Steurer, Frank J. and Breitschwerdt, Edward B.}, year={1993}, month={Jan}, pages={16–19} }
 @article{sellon_rottman_jordan_wells_simpson_nelson_keene_1992, title={Hypereosinophilia associated with transitional cell carcinoma in a cat}, volume={201}, number={4}, journal={Journal of the American Veterinary Medical Association}, author={Sellon, R. K. and Rottman, J. B. and Jordan, H. L. and Wells, M. R. and Simpson, R. M. and Nelson, P. and Keene, B. W.}, year={1992}, pages={591} }
 @article{sellon_atkins_hardie_1992, title={Variable rate pacing and terbutaline in the treatment of syncope associated with second-degree atrioventricular block in a dog}, volume={28}, number={4}, journal={Journal of the American Animal Hospital Association}, author={Sellon, R. K. and Atkins, C. E. and Hardie, E. M.}, year={1992}, pages={311} }