@article{baneth_weigler_1997, title={Retrospective case-control study of hepatozoonosis in dogs in Israel}, volume={11}, DOI={10.1111/j.1939-1676.1997.tb00482.x}, abstractNote={Signalment, clinical signs, and physical examination and clinicopathologic findings in dogs diagnosed withHepatozoon cam'sparasitemia (n = 100) were compared with those inHepatozoon‐negative dogs (n = 180). A subset (n = 15) ofHepatozoon‐positive dogs with unusually high (> 800H canisgametocytes/μL of whole blood) parasitemia was compared with dogs that had low parasitemia (n = 85) and with Hepatozoon‐negative dogs (n = 180).Hepatozoon‐positive dogs significantly differed from Hepatozoon‐negative dogs in body temperature, total red blood cell count, hemoglobin concentration, hematocrit, and platelet count. Dogs with highH canisparasitemia significantly differed from those with low parasitemia in hemoglobin concentration, hematocrit, and total neutrophil count. Clinical findings from dogs with highH canisparasitemia included emaciation, lethargy, hyperglobulinemia, hypoalbuminemia, and increased serum alkaline phosphatase and creatine kinase activities. Findings at necropsy included hepatitis, pneumonia, and glomerulonephritis associated withH canisschizonts and extensive parasitism of bone marrow, spleen, and lymph nodes. Low hemoglobin concentration, low platelet count, and concurrent parvovirus infection together represented the best predictor variables forHepatozoonpositivity in dogs presenting to the hospital.}, number={6}, journal={Journal of Veterinary Internal Medicine}, author={Baneth, G. and Weigler, B.}, year={1997}, pages={365–370} }
 @article{baneth_kordick_hegarty_breitschwerdt_1996, title={Comparative seroreactivity to Bartonella henselae and Bartonella quintana among cats from Israel and North Carolina}, volume={50}, ISSN={0378-1135}, url={http://dx.doi.org/10.1016/0378-1135(96)00006-5}, DOI={10.1016/0378-1135(96)00006-5}, abstractNote={Bartonella henselae, the predominant cause of cat scratch disease, and Bartonella quintana, the cause of trench fever, are closely related Bartonella species that induce cross-reactivity when cat or human sera are tested using an indirect immunofluorescence antibody (IFA) test. Cats are the natural reservoir for B. henselae, whereas a mammalian reservoir host for B. quintana has not been identified. Serum samples from 114 cats from Israel and 114 cats from North Carolina were tested by IFA for seroreactivity to B. henselae and B. quintana antigens. Similar numbers of cats from Israel [45 (39.5%)] and from North Carolina [46 (40.4%)] were seroreactive to both antigens, however, as compared to cats from North Carolina [8 (7%)], a significantly (P = 0.001) larger number of cats from Israel were seroreactive to B. quintana antigen only [23 (20.2%)]. In addition, mean antibody titers were lower to B. henselae than to B. quintana (P = 0.0001) in the cats from Israel, whereas similar mean titers to both antigens were identified in cats from North Carolina. Absorption of serum using whole B. henselae organisms resulted in a significantly greater (P = 0.0001) decreacse in antibody titer to B. henselae between absorbed and non-absorbed sera, as compared to the decrease in antibody titer following absorption with whole B. quintana organisms. There was a similar decrease in antibody titer in sera from cats experimentally infected with B. henselae and in cats naturally exposed to Bartonella species from Israel and North Carolina. Our results indicate that absorption of serum will, in most instances, distinguish species-specific reactivity by IFA to B. henselae from cross-reactivity to B. quintana in cats experimentally infected with B. henselae. The data support the conclusion that B. henselae is the principal Bartonella species responsible for seroreactivity against B. henselae and B. quintana in naturally exposed cats from Israel or North Carolina. It also suggests that in Israel, cats are exposed to one or more antigenically different Bartonella species, sub-species or strains, that seroreact by IFA more intensely with B. quintana antigen.}, number={1-2}, journal={Veterinary Microbiology}, publisher={Elsevier BV}, author={Baneth, Gad and Kordick, Dorsey L. and Hegarty, Barbara C. and Breitschwerdt, Edward B.}, year={1996}, month={May}, pages={95–103} }