@article{jesudason_anspaugh_roe_1992, title={JUVENILE-HORMONE METABOLISM IN THE PLASMA, INTEGUMENT, MIDGUT, FAT-BODY, AND BRAIN DURING THE LAST INSTAR OF THE TOBACCO HORNWORM, MANDUCA SEXTA (L)}, volume={20}, ISSN={["0739-4462"]}, DOI={10.1002/arch.940200202}, abstractNote={Abstract}, number={2}, journal={ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY}, author={JESUDASON, P and ANSPAUGH, DD and ROE, RM}, year={1992}, pages={87–105} }
 @article{jesudason_venkatesh_roe_1990, title={HEMOLYMPH JUVENILE-HORMONE ESTERASE DURING THE LIFE-CYCLE OF THE TOBACCO HORNWORM, MANDUCA-SEXTA (L)}, volume={20}, ISSN={["0020-1790"]}, DOI={10.1016/0020-1790(90)90071-2}, abstractNote={Juvenile hormone (JH) esterase activity was found in the plasma of larvae, pupae and adults of wild-type tobacco hornworms, Manduca sexta. There was a single peak of plasma JH esterase activity approx. 28 h prior to ecdysis in each instar from the second through the fourth instar and a peak of activity prior to both wandering and pupation in the fifth (last) instar. JH esterase activity was high in newly formed male and female pupae but declined to minimal levels by day 1 of the pupal stage. For the remainder of the pupal period, activity was at background levels. JH esterase activity increased again in newly emerged, virgin male and female adults but declined and remained at a low level 1 day after emergence through death. Gel filtration analysis of larval, pupal and adult plasma resolved a single peak of JH esterase activity with an apparent molecular weight of 66,000. However, isoelectric focusing revealed three forms with isoelectric points of 5.5, 5.8 and 6.1. These isoelectric forms were also found in black and white mutants of last instar M. sexta and in purified JH esterase from wild-type larvae. The plasma JH esterase activity metabolized JH I 2–3 times faster than JH III and was sensitive to inhibition by octylthio-1,1,1-trifluoro-2-propanone and insensitive to O,O-diisopropyl phosphorofluoridate. Gel filtration, isoelectric focusing, substrate specificity and developmental studies suggest that the same JH esterases are found in the plasma of larvae, pupae and adults and appear to be different from general (α-NA) esterase.}, number={6}, journal={INSECT BIOCHEMISTRY}, author={JESUDASON, P and VENKATESH, K and ROE, RM}, year={1990}, pages={593–604} }
 @article{jesudason_levi_weiden_roe_1988, title={DEVELOPMENTAL-CHANGES IN THE MICROSOMAL MONOOXYGENASE SYSTEM AND THE INVIVO METABOLISM OF ALDRIN IN LARVAE OF THE MEXICAN BEAN BEETLE (COLEOPTERA, COCCINELLIDAE)}, volume={81}, ISSN={["1938-291X"]}, DOI={10.1093/jee/81.6.1598}, abstractNote={In vivo metabolism of topically applied aldrin and the specific levels of whole body and abdominal microsomal cytochrome P-450, P-420, b5 and creductase were measured during development in the penultimate and last instar of the Mexican bean beetle, Epilachna varivestis Mulsant. There were no significant differences between molting larvae (from the penultimate to the last instar), last-instar feeding larvae and prepupae in these monooxygenase properties for whole-body microsomal preparations, and in respect to in vivo metabolism. Cytochrome P-450, b5, and creductase were higher in the abdominal microsomes of feeding-stage larvae than in whole-body microsomes from the same stage, and cytochrome P-450 and b5 were higher in the abdominal microsomes of feeding-stage larvae than in the abdominal microsomes from prepupae. The molar ratio of P-450 to P-420 was constant (approximately 1) for all microsomal preparations examined. The high tolerance of Mexican bean beetle larvae to topically applied aldrin could not be predicted based on poor penetration or the inability of aldrin to be epoxidized to dieldrin.}, number={6}, journal={JOURNAL OF ECONOMIC ENTOMOLOGY}, author={JESUDASON, P and LEVI, PE and WEIDEN, M and ROE, RM}, year={1988}, month={Dec}, pages={1598–1605} }