@article{jesudason_anspaugh_roe_1992, title={JUVENILE-HORMONE METABOLISM IN THE PLASMA, INTEGUMENT, MIDGUT, FAT-BODY, AND BRAIN DURING THE LAST INSTAR OF THE TOBACCO HORNWORM, MANDUCA SEXTA (L)}, volume={20}, ISSN={["0739-4462"]}, DOI={10.1002/arch.940200202}, abstractNote={Abstract Juvenile hormone (JH) III esterase and JH III epoxide hydrolase activity was found in the integument, midgut, fat body, and brain during last instar development of the tobacco hornworm, Manduca sexta . JH esterase activity was primarily located in the cytosol in these tissues while the majority of the JH epoxide hydrolase activity was found in the microsomes. A prewandering (on day 3) and postwandering (on day 8) peak in plasma JH III esterase activity occurs in the last instar of gate I M. sexta . The JH esterase activity profile in integument, midgut, fat body, and brain followed a similar pattern to that of the plasma. The only exception to this was the absence of the postwandering, prepupal (on day 8) JH esterase peak in the fat body. The topical application of the juvenoid, (RS)‐methoprene, failed to induce fat body JH esterase activity but increased activity in the plasma, integument, midgut, and brain in M. sexta prepupae. These results indicate that the source of plasma JH esterase activity is not always the fat body as previously hypothesized. The developmental profile of tissue JH epoxide hydrolase activity was also similar to that of JH esterase suggesting that both enzymes may be regulated partly by the same factors and that JH epoxide hydrolase may also have an important, previously unrecognized functional role in JH regulation and insect metamorphosis. Multiple isoelectric forms of tissue‐specific JH esterases and JH epoxide hydrolases were found in integument, midgut, fat body, and brain. The JH esterases in these tissues had isoelectric points more acidic than that for plasma. Tissue α‐naphthyl acetate esterase, developmental profiles, and inhibitor sensitivity to 3‐(octylthio)‐1,1,1‐trifluoropropan‐2‐one differed significantly from that for JH esterase, suggesting that they represent different enzymes. ©1992 Wiley‐Liss, Inc.}, number={2}, journal={ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY}, author={JESUDASON, P and ANSPAUGH, DD and ROE, RM}, year={1992}, pages={87–105} }
 @article{jesudason_venkatesh_roe_1990, title={HEMOLYMPH JUVENILE-HORMONE ESTERASE DURING THE LIFE-CYCLE OF THE TOBACCO HORNWORM, MANDUCA-SEXTA (L)}, volume={20}, ISSN={["0020-1790"]}, DOI={10.1016/0020-1790(90)90071-2}, abstractNote={Juvenile hormone (JH) esterase activity was found in the plasma of larvae, pupae and adults of wild-type tobacco hornworms, Manduca sexta. There was a single peak of plasma JH esterase activity approx. 28 h prior to ecdysis in each instar from the second through the fourth instar and a peak of activity prior to both wandering and pupation in the fifth (last) instar. JH esterase activity was high in newly formed male and female pupae but declined to minimal levels by day 1 of the pupal stage. For the remainder of the pupal period, activity was at background levels. JH esterase activity increased again in newly emerged, virgin male and female adults but declined and remained at a low level 1 day after emergence through death. Gel filtration analysis of larval, pupal and adult plasma resolved a single peak of JH esterase activity with an apparent molecular weight of 66,000. However, isoelectric focusing revealed three forms with isoelectric points of 5.5, 5.8 and 6.1. These isoelectric forms were also found in black and white mutants of last instar M. sexta and in purified JH esterase from wild-type larvae. The plasma JH esterase activity metabolized JH I 2–3 times faster than JH III and was sensitive to inhibition by octylthio-1,1,1-trifluoro-2-propanone and insensitive to O,O-diisopropyl phosphorofluoridate. Gel filtration, isoelectric focusing, substrate specificity and developmental studies suggest that the same JH esterases are found in the plasma of larvae, pupae and adults and appear to be different from general (α-NA) esterase.}, number={6}, journal={INSECT BIOCHEMISTRY}, author={JESUDASON, P and VENKATESH, K and ROE, RM}, year={1990}, pages={593–604} }
 @article{jesudason_levi_weiden_roe_1988, title={DEVELOPMENTAL-CHANGES IN THE MICROSOMAL MONOOXYGENASE SYSTEM AND THE INVIVO METABOLISM OF ALDRIN IN LARVAE OF THE MEXICAN BEAN BEETLE (COLEOPTERA, COCCINELLIDAE)}, volume={81}, ISSN={["1938-291X"]}, DOI={10.1093/jee/81.6.1598}, abstractNote={Journal Article Developmental Changes in the Microsomal Monooxygenase System and the In Vivo Metabolism of Aldrin in Larvae of the Mexican Bean Beetle (Coleoptera: Coccinellidae) Get access Princy Jesudason, Princy Jesudason Search for other works by this author on: Oxford Academic PubMed Google Scholar Patricia E. Levi, Patricia E. Levi Search for other works by this author on: Oxford Academic PubMed Google Scholar Mathias Weiden, Mathias Weiden Search for other works by this author on: Oxford Academic PubMed Google Scholar Michael R. Roe Michael R. Roe Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 81, Issue 6, 1 December 1988, Pages 1598–1605, https://doi.org/10.1093/jee/81.6.1598 Published: 01 December 1988 Article history Received: 27 October 1987 Accepted: 12 July 1988 Published: 01 December 1988}, number={6}, journal={JOURNAL OF ECONOMIC ENTOMOLOGY}, author={JESUDASON, P and LEVI, PE and WEIDEN, M and ROE, RM}, year={1988}, month={Dec}, pages={1598–1605} }