@article{adler_jiang_dye_dreher_1998, title={Exposure of differentiated rodent airway epithelial cells in vitro to particles of residual fly ash (ROFA) induces cytotoxicity and generation of reactive oxygen species.}, volume={10}, journal={Proceedings of the 10th International Colloquium on Lung Fibrosis}, author={Adler, K. B. and Jiang, N. F. and Dye, J. A. and Dreher, K. L.}, year={1998}, pages={26} } @article{jiang_cockerham_moll_1990, title={INTERCULTIVAR AND INTRACULTIVAR EFFECTS OF SELECTION ON HETEROSIS}, volume={30}, ISSN={["0011-183X"]}, DOI={10.2135/cropsci1990.0011183X003000010010x}, abstractNote={The effect of selection on heterosis depends on the gene action and the type of selection. Intracultivar (W) selection, full‐sib family selection within each of two cultivars, and intercultivar (R) selection, reciprocal recurrent selection between the two cultivars, were contrasted for their effects on heterosis. The cultivars were considered to be random replicate populations from an ancestral population. The relatedness of individuals within cultivars and the degree of divergence between cultivars were formalized in terms of identity by descent (IBD) measures for two, three, two‐pair, and four genes a locus and joint IBD measures for genes at each of two loci. Quantitative genetic components for a model that is general for additive, dominance, and additive by additive (a ✕ a) effects with an arbitrary number of alleles were defined for the ancestral population, and selection responses were formulated for the cultivars and the hybrid for each selection method with the aid of the IBD measures. A further analysis was made utilizing a biological building block model of gene effects. The contribution of a ✕ a effects was such that they reduced heterosis from W selection, but slightly increased heterosis from R selection. It was concluded that R selection always increased heterosis while W selection could increase or decrease heterosis, but decreased heterosis for a preponderance of the genetic parameters considered.}, number={1}, journal={CROP SCIENCE}, author={JIANG, CJ and COCKERHAM, CC and MOLL, RH}, year={1990}, pages={44–49} } @article{jiang_cockerham_1990, title={QUANTITATIVE GENETIC COMPONENTS WITHIN RESTRICTED POPULATIONS}, volume={30}, ISSN={["0011-183X"]}, DOI={10.2135/cropsci1990.0011183X003000010002x}, abstractNote={Breeders often work with populations with a restricted genetic base either from the maintenance of varieties as small finite populations or from the initiation of populations with a few individuals or inbred lines. It is important to know the consequences of these restrictions on quantitative variation in comparison to that for large noninbred populations. To accomplish this the quantitative genetic variation within restricted populations is formulated in terms of the quantitative genetic components in the noninbred ancestral population. Required to treat an additive, dominance and additive by additive model are six components: σ2a‐additive variance, σ2d‐dominance variance, d1‐covariance of additive and homozygous dominance effects, d2‐variance of homozygous dominance effects, h2‐ square of the inbreeding effect, and σ2aa‐additive by additive variance. Comparable components (starred, e.g. σ2a*) for restricted populations, as an average over replicates, are expressed as linear functions of the components in the ancestral population with coefficients of identity by descent measures. These results from operating directly on the effects and variances within populations for all the components confirm previous results from covariances of relatives for σ2a* and σ2d*. Examples of further self‐fertilization and of a few inbred founders are considered in some detail. In the latter case considerable simplification occurs in that all coefficients are functions of the coancestry coefficient. While it is informative to relate the quantitative genetic components in restricted populations to those in ancestral populations, there is no practical advantage over just defining the components for a specific population when attention is to be confined to that population.}, number={1}, journal={CROP SCIENCE}, author={JIANG, CJ and COCKERHAM, CC}, year={1990}, pages={7–12} }