@article{johnson_welsh_juniewicz_1982, title={SUPPRESSION OF LUTEINIZING-HORMONE AND TESTOSTERONE SECRETION IN BULLS FOLLOWING ADRENOCORTICOTROPIN HORMONE-TREATMENT}, volume={26}, ISSN={["1529-7268"]}, DOI={10.1095/biolreprod26.2.305}, abstractNote={The present investigation was conducted to evaluate the inhibitory effects of adrenal corticosteroids on testosterone production by the bull testis. Administration of a single i.v. dose of adrenocorticotropic hormone (ACTH; 80 IU) resulted in a corticosteroid peak which lasted approximately 6 h. During this 6 h period, no episodic increases in secretion of LH or testosterone were initiated and basal concentrations of testosterone were suppressed (P less than 0.05) below control values. Episodic secretion of LH and testosterone resumed 6--7 h after ACTH when concentrations of serum corticosteroids had returned to basal levels. These results suggest that ACTH-induced increases in serum corticosteroids suppress the episodic secretion of LH, resulting in a suppression of testosterone secretion by the bull testis.}, number={2}, journal={BIOLOGY OF REPRODUCTION}, author={JOHNSON, BH and WELSH, TH and JUNIEWICZ, PE}, year={1982}, pages={305–310} } @article{johnson_eisen_1975, title={EFFECTS OF SELECTION FOR POSTWEANING GAIN ON TESTICULAR FUNCTION IN MICE}, volume={17}, ISSN={["0008-4093"]}, DOI={10.1139/g75-010}, abstractNote={Changes in testicular and epididymal function and selected endocrine organ size were examined in a line of mice selected for rapid postweaning gain (M16) and in reciprocal crosses with an unselected pedigree control line (ICR). The larger body weight of the M16 line was accompanied by larger testes, epididymides, seminal vesicle, pituitary, thyroid and adrenal weights (P <.01) although the testes, epididymides, seminal vesicle and adrenal weights of M16 mice, expressed per gram body weight, actually decreased (P <.01) relative to the ICR line. Testicular and epididymal sperm reserves were higher in M16 mice but the difference was not significant. However, when adjusted for gland size, testicular and epididymal sperm reserves were lower in the M16 line (P <.01). Absolute and relative weights of testes, epididymides and pituitary were larger (P <.01) in M16 ♀ × ICR ♂ crosses than in ICR ♀ × M16 ♂ crosses. Although testicular and epididymal sperm reserves were higher in M16 ♀ × ICR ♂ males the reciprocal difference was significant only for testicular sperm (P <.05). Heterotic effects were significant for both absolute and relative weights of testes, epididymides (P <.01), pituitary (P <.05) and relative weight of seminal vesicles (P <.05). Although percent heterosis was 8.5 for testicular and epididymal sperm reserves, significant heterotic effects were found only for epididymal sperm (P <.05).}, number={1}, journal={CANADIAN JOURNAL OF GENETICS AND CYTOLOGY}, author={JOHNSON, BH and EISEN, EJ}, year={1975}, pages={93–104} }