J. Ma

Works (1)

Updated: July 5th, 2023 15:53

1995 journal article

Tumor necrosis factor-α responses are depressed and interleukin-6 responses unaltered in feline immunodeficiency virus infected cats

Veterinary Immunology and Immunopathology, 46(1-2), 35–50.

By: J. Ma n, S. Kennedy-Stoskopf n, R. Sellon n, S. Tonkonogy n, E. Hawkins n , M. Tompkins n, W. Tompkins n

MeSH headings : Animals; Bronchoalveolar Lavage Fluid / cytology; CD4-Positive T-Lymphocytes; Cats; Cells, Cultured; Feline Acquired Immunodeficiency Syndrome / metabolism; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / isolation & purification; In Situ Hybridization / veterinary; Interleukin-6 / biosynthesis; Leukocytes, Mononuclear / metabolism; Lipopolysaccharides / pharmacology; Lymphocyte Activation / drug effects; Macrophages, Alveolar / virology; Mitogens / pharmacology; RNA, Messenger / analysis; RNA, Viral / analysis; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha / biosynthesis
TL;DR: Feline immunodeficiency virus could be recovered from the culture supernatants of BAL cells from infected cats by co-cultivation with susceptible lymphocytes, and in situ hybridization identified FIV mRNA in a small fraction of alveolar macrophages in the BAL cell cultures. (via Semantic Scholar)
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