Weiqing Zhou

Works (1)

Updated: July 5th, 2023 16:01

2000 article

Evaluation of the Binding between Potential Anti-HIV DNA-Based Drugs and Viral Envelope Glycoprotein gp120 by Capillary Electrophoresis with Laser-Induced Fluorescence Detection

Zhou, W., Tomer, K. B., & Khaledi, M. G. (2000, September 1). Analytical Biochemistry.

By: W. Zhou n, K. Tomer* & M. Khaledi n

author keywords: phosphorothioate oligodeoxynucleotide; HIV envelope glycoprotein gp120; affinity-capillary electrophoresis; laser-induced fluorescence detection
MeSH headings : Anti-HIV Agents / metabolism; Base Sequence; Binding, Competitive; DNA Primers; Electrophoresis, Capillary / methods; Evaluation Studies as Topic; HIV Envelope Protein gp120 / metabolism; HIV-1 / metabolism; Lasers; Protein Binding; Spectrometry, Fluorescence
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HIV Research and Treatment; Advanced biosensing and bioanalysis techniques
TL;DR: Capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) was used to systematically evaluate binding between Sd and HIV-1 gp120 and showed that the interaction had a strong dependence on the sulfur phosphorothioate backbone. (via Semantic Scholar)
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Added: August 6, 2018

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