Works (1)
Updated: July 5th, 2023 16:01
2000 journal article
Evaluation of the binding between potential anti-HIV DNA-based drugs and viral envelope glycoprotein gp120 by capillary electrophoresis with laser-induced fluorescence detection
ANALYTICAL BIOCHEMISTRY, 284(2), 334–341.
author keywords: phosphorothioate oligodeoxynucleotide; HIV envelope glycoprotein gp120; affinity-capillary electrophoresis; laser-induced fluorescence detection
MeSH headings : Anti-HIV Agents / metabolism; Base Sequence; Binding, Competitive; DNA Primers; Electrophoresis, Capillary / methods; Evaluation Studies as Topic; HIV Envelope Protein gp120 / metabolism; HIV-1 / metabolism; Lasers; Protein Binding; Spectrometry, Fluorescence
TL;DR:
Capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) was used to systematically evaluate binding between Sd and HIV-1 gp120 and showed that the interaction had a strong dependence on the sulfur phosphorothioate backbone.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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