@article{mcentee_horton_blue_meuten_1993, title={GRANULATED ROUND CELL TUMOR OF CATS}, volume={30}, ISSN={["0300-9858"]}, DOI={10.1177/030098589303000213}, abstractNote={Morphologic and biologic features of five feline granulated round cell tumors were compared with those previously reported to be of globule leukocyte and large granular lymphocyte origin. The five cats ranged from 6 to 9 years of age and presented with nonspecific gastrointestinal signs. Four of the five cats were tested for feline leukemia virus and were negative by enzyme-linked immunosorbent assay. The neoplastic process involved the abdominal cavity in all cases, with a predilection for the distal small intestine and mesentery. The liver and peripheral and thoracic lymphoid tissues were also sporadically affected. Neoplastic round cells contained 0.5–1.5-μm eosinophilic cytoplasmic granules that were difficult to discern on casual observation with hematoxylin and eosin stain but were deep blue and easily visualized when stained with phosphotungstic acid-hematoxylin. In two cases, epithelium in the affected ileum and liver contained unusually large numbers of apparently normal globule leukocytes. Ultrastructurally, the tumor granules tended to cluster at one nuclear pole and were spindle to round in shape with variably dense contents. Some granules contained a dense “cap” at one end or internal crystalloid bars that distorted the granule membrane. The tumors reported herein are similar to all three of the previously reported feline granulated round cell tumors and probably have a common cellular origin.}, number={2}, journal={VETERINARY PATHOLOGY}, author={MCENTEE, MF and HORTON, S and BLUE, J and MEUTEN, DJ}, year={1993}, month={Mar}, pages={195–203} } @article{mcentee_ficken_1990, title={BLOOD CLEARANCE OF RADIOLABELED GOLD COLLOID BY THE TURKEY MONONUCLEAR PHAGOCYTIC SYSTEM}, volume={34}, ISSN={["0005-2086"]}, DOI={10.2307/1591426}, abstractNote={Radiolabeled gold colloid (198Au), which has been used to assess particle clearance in mammalian species, was used to assess blood-borne particle clearance in turkeys. When turkeys 16 weeks of age were injected intravenously with these particles, there was greater than a 98% decrease in blood gamma emission from 1 minute to 6 minutes postinjection. Uptake of particles was predominantly hepatic with minor uptake by the spleen and bone marrow. Negligible uptake was observed in lung, kidney, and skeletal muscle. Autoradiography demonstrated particles within Kupffer cells of the liver, periarteriolar macrophages of the spleen, and bone-marrow macrophages. Particles could not be demonstrated within the lung or kidney. The mononuclear phagocyte system responsible for blood particle clearance in turkeys is therefore located predominantly within the liver, spleen, and bone marrow and is similar to that of rats, mice, rabbits, and dogs. Pulmonary intravascular macrophages, which have recently been described in ruminants and pigs, are not apparent in this species.}, number={2}, journal={AVIAN DISEASES}, author={MCENTEE, MF and FICKEN, MD}, year={1990}, pages={393–397} }