2009 journal article

Investigations on the nature and pathogenicity of circulating antikeratinocyte antibodies in dogs with pemphigus foliaceus


By: T. Olivry n, S. Dunston n, R. Walker n, Z. Alhaidari, L. Messinger & Z. Liu*

Contributors: T. Olivry n, S. Dunston n, R. Walker n, Z. Alhaidari, L. Messinger & Z. Liu*

MeSH headings : Animals; Animals, Newborn; Antibody Specificity; Blister / immunology; Dog Diseases / immunology; Dogs; Epidermis / metabolism; Immunization, Passive; Immunoglobulin G / blood; Keratinocytes / immunology; Mice; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary; Protein Binding
TL;DR: It is suggested that antikeratinocyte IgG4 antibodies could be relevant to disease pathogenesis because canine PF or PV IgG appear to be pathogenic when transferred passively into mice, causing vesiculation at epidermal levels similar to those of the natural disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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