Robina H. Walker

Works (1)

Updated: July 5th, 2023 15:51

2008 journal article

Investigations on the nature and pathogenicity of circulating antikeratinocyte antibodies in dogs with pemphigus foliaceus

VETERINARY DERMATOLOGY, 20(1), 42–50.

By: T. Olivry n , S. Dunston n, R. Walker n, Z. Alhaidari, L. Messinger & Z. Liu *

Contributors: T. Olivry n , S. Dunston n, R. Walker n, Z. Alhaidari, L. Messinger & Z. Liu *

MeSH headings : Animals; Animals, Newborn; Antibody Specificity; Blister / immunology; Dog Diseases / immunology; Dogs; Epidermis / metabolism; Immunization, Passive; Immunoglobulin G / blood; Keratinocytes / immunology; Mice; Pemphigus / blood; Pemphigus / immunology; Pemphigus / veterinary; Protein Binding
TL;DR: It is suggested that antikeratinocyte IgG4 antibodies could be relevant to disease pathogenesis because canine PF or PV IgG appear to be pathogenic when transferred passively into mice, causing vesiculation at epidermal levels similar to those of the natural disease. (via Semantic Scholar)
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