Predictive Modeling of a Mixture of Thyroid Hormone Disrupting Chemicals That Affect Production and Clearance of Thyroxine
INTERNATIONAL JOURNAL OF TOXICOLOGY, 28(5), 368–381.
United States of America 🇺🇸
author keywords: thyroid hormone disruption; mixture modeling; pronamide; mancozeb; thiram; polyhalogenated aromatic hydrocarbons
MeSH headings :
Animals; Cytochrome P-450 CYP1A1 / metabolism; Cytochrome P-450 CYP2B1 / metabolism; Dose-Response Relationship, Drug; Endocrine Disruptors / chemistry; Endocrine Disruptors / toxicity; Female; Microsomes, Liver / drug effects; Microsomes, Liver / enzymology; Models, Biological; Pesticides / chemistry; Pesticides / toxicity; Predictive Value of Tests; Rats; Rats, Long-Evans; Thyroid Gland / drug effects; Thyroid Gland / metabolism; Thyroxine / biosynthesis; Thyroxine / blood; Thyroxine / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018