Works (7)

2014 journal article

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

MOLECULAR SYSTEMS BIOLOGY, 10(1).

author keywords: growth factor receptors; mitogen-activated protein kinases; negative feedback; nucleocytoplasmic shuttling; mathematical model
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K-and Ras-dependent ERK activation

BIOCHEMICAL JOURNAL, 441(1), 77–85.

By: M. Cirit & J. Haugh

author keywords: computational biology; cross-talk; growth factor; kinetic analysis; mitogen-activated protein kinase (MAPK); receptor tyrosine kinase
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

PLOS ONE, 7(11).

By: M. Cirit, K. Grant & J. Haugh

Ed(s): L. Buday

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase

JOURNAL OF BIOLOGICAL CHEMISTRY, 286(5), 3323–3331.

By: G. Buhrman, V. Kumar*, M. Cirit, J. Haugh & C. Mattos

Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 article

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk (vol 5, pg 246, 2009)

Wang, C.-C., Cirit, M., & Haugh, J. M. (2011, August). MOLECULAR SYSTEMS BIOLOGY, Vol. 7.

By: C. Wang, M. Cirit & J. Haugh

Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells

PLOS COMPUTATIONAL BIOLOGY, 6(2).

By: M. Cirit, M. Krajcovic, C. Choi*, E. Welf, A. Horwitz* & J. Haugh

Ed(s): A. Asthagiri

Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network

JOURNAL OF BIOLOGICAL CHEMISTRY, 285(47), 36736–36744.

By: M. Cirit, C. Wang & J. Haugh

Sources: Web Of Science, ORCID
Added: August 6, 2018