Murat Cirit

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

Molecular Systems Biology, 10(1).

Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K-and Ras-dependent ERK activation

Biochemical Journal (London, England : 1984), 441, 77–85.

Systemic perturbation of the ERK signaling pathway by the proteasome inhibitor, MG132

PLoS One, 7(11).

Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase

Journal of Biological Chemistry, 286(5), 3323–3331.

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk (vol 5, pg 246, 2009)

Molecular Systems Biology, Vol. 7.

Stochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells

PLoS Computational Biology, 6(2).

Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network

Journal of Biological Chemistry, 285(47), 36736–36744.