A. J. Harris
Works (3)
Updated: July 5th, 2023 15:49
2011 journal article
A facile synthesis of 1,5-disubstituted-2-aminoimidazoles: Antibiotic activity of a first generation library
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21(15), 4516–4519.
author keywords: 2-Aminoimidazole; Amino aldehyde; Biofilm; Antibiotic
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Drug Resistance, Multiple, Bacterial / drug effects; Imidazoles / chemical synthesis; Imidazoles / chemistry; Imidazoles / pharmacology; Microbial Sensitivity Tests; Structure-Activity Relationship
TL;DR:
An efficient synthetic route to 1,5-disubstituted 2-aminoimidazoles from readily available amino acids and aldehydes has been developed and several compounds were shown to exhibit notable antibiotic activity against a variety of bacterial strains including multi-drug resistant isolates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Estimating ancestral distributions of lineages with uncertain sister groups: a statistical approach to Dispersal-Vicariance Analysis and a case using Aesculus L. (Sapindaceae) including fossils
Journal of Systematics and Evolution, 47(5), 349–368.
author keywords: Aesculus; biogeography; DIVA; fossil wildcards; MrBayes; phylogenetic uncertainty
TL;DR:
The DIVA‐Bayes approach to infer biogeographic histories without fully bifurcating trees was tested using Aesculus L., which has major lineages unresolved as a polytomy, and it was found that adding fossil wildcard taxa in phylogenetic analysis generally increased P for ancestral ranges including the fossil's distribution area.
(via Semantic Scholar)
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Phylogeny, origin, and biogeographic history of Aesculus L. (Sapindales) - an update from combined analysis of DNA sequences, morphology, and fossils
Taxon, 58(1), 108–126.
Source: NC State University Libraries
Added: August 6, 2018
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