1997 journal article

Auto IgG anti-IgE and IgG x IgE immune complex presence and effects on ELISA-based quantitation of IgE in canine atopic dermatitis, demodectic acariasis and helminthiasis.


By: B. Hammerberg n, D. Bevier n, D. DeBoer*, T. Olivry n, S. Orton n, D. Gebhard n, S. Vaden n

Contributors: B. Hammerberg n, D. Bevier n, D. DeBoer*, T. Olivry n, S. Orton n, D. Gebhard n, S. Vaden n

author keywords: auto anti-IgE; ELISA; atopic; helminth; immune complexes; demodectic acariasis
MeSH headings : Animals; Antibodies, Anti-Idiotypic / blood; Antigen-Antibody Complex / blood; Ascariasis / immunology; Ascariasis / veterinary; Autoantibodies / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Helminthiasis, Animal / immunology; Immunoglobulin E / blood; Immunoglobulin G / blood
TL;DR: The increase in detectable IgG anti-IgE after heating sera indicates that IgG x IgE immune complexes are normally present in most dogs; however, the increase over uncomplexed IgG against IgE was most pronounced in dogs manifesting atopic dermatitis and demodectic acariasis. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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