Auto IgG anti-IgE and IgG × IgE immune complex presence and effects on ELISA-based quantitation of IgE in canine atopic dermatitis, demodectic acariasis and helminthiasis
Hammerberg, B., Bevier, D., DeBoer, D. J., Olivry, T., Orton, S. M., Gebhard, D., & Vaden, S. L. (1997, December 1). Veterinary Immunology and Immunopathology, Vol. 60, pp. 33–46.
author keywords: auto anti-IgE; ELISA; atopic; helminth; immune complexes; demodectic acariasis
MeSH headings : Animals; Antibodies, Anti-Idiotypic / blood; Antigen-Antibody Complex / blood; Ascariasis / immunology; Ascariasis / veterinary; Autoantibodies / blood; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Dog Diseases / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Helminthiasis, Animal / immunology; Immunoglobulin E / blood; Immunoglobulin G / blood
topics (OpenAlex): Dermatology and Skin Diseases; Allergic Rhinitis and Sensitization; T-cell and B-cell Immunology
TL;DR:
The increase in detectable IgG anti-IgE after heating sera indicates that IgG x IgE immune complexes are normally present in most dogs; however, the increase over uncomplexed IgG against IgE was most pronounced in dogs manifesting atopic dermatitis and demodectic acariasis.
(via
Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries