Works (1)
Updated: July 30th, 2023 21:14
2009 journal article
SNP Selection and Multidimensional Scaling to Quantify Population Structure
GENETIC EPIDEMIOLOGY, 33(6), 488–496.
author keywords: population stratification; substructure-informative SNP selection; Hardy-Weinberg disequilibrium; nonmetric MDS; association studies
MeSH headings : Algorithms; Genetic Markers; Genetics, Population / methods; Genome-Wide Association Study; Humans; Polymorphism, Single Nucleotide; Selection, Genetic
TL;DR:
This work develops methodology for single nucleotide polymorphism (SNP) selection and subsequent population stratification visualization based on deviation from Hardy‐Weinberg equilibrium in conjunction with non‐metric multidimensional scaling (MDS); a distance‐based multivariate technique.
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