@misc{daub_ehrenshaft_jenns_2000, title={Isolated genes and proteins encoding resistance to photosensitizers}, volume={6,063,987}, number={2000 May 16}, publisher={Washington, DC: U.S. Patent and Trademark Office}, author={Daub, M. E. and Ehrenshaft, M. and Jenns, A. E.}, year={2000} }
 @article{chung_jenns_ehrenshaft_daub_1999, title={A novel gene required for cercosporin toxin resistance in the fungus Cercospora nicotianae}, volume={262}, DOI={10.1007/pl00008642}, abstractNote={Cercosporin, a photosensitizing perylenequinone toxin produced by the plant pathogenic Cercospora fungi, generates the highly toxic singlet oxygen (1O2) upon exposure to light. Cercosporin shows broad toxicity against a wide range of organisms, including bacteria, fungi, plants, and animals; however, Cercospora fungi are resistant to its effects. A novel gene, crg1 (cercosporin-resistance gene) was isolated from a wild-type strain of C. nicotianae by genetic complementation of a C. nicotianae mutant (CS10) which is cercosporin sensitive and down-regulated in cercosporin production. Sequence analysis indicated that crg1 encodes a putative protein of 550 amino acids with four putative transmembrane helical regions, however CRG1 shows no strong similarity to any other protein in sequence databases. Northern analysis identified two transcripts (4.5 and 2.6 kb) that are unaffected by the presence of light or cercosporin. Southern analysis demonstrated that crg1 is present in a single copy in the C. nicotianae genome and can be detected only in Cercospora species. Targeted disruption of crg1 resulted in mutants that, like CS10, are sensitive to cercosporin. However, unlike CS10, crg1 disruption mutants are not down-regulated in toxin production. Both CS10 and the crg1 disruption mutants are unaffected in their response to other 1O2-generating photosensitizers, suggesting that CRG1 functions specifically against cercosporin, rather than against 1O2.}, number={2}, journal={Molecular and General Genetics}, author={Chung, K. R. and Jenns, A. E. and Ehrenshaft, M. and Daub, M. E.}, year={1999}, pages={382–389} }
 @article{ehrenshaft_chung_jenns_daub_1999, title={Functional characterization of SOR1, a gene required for resistance to photosensitizing toxins in the fungus Cercospora nicotianae}, volume={34}, ISSN={["0172-8083"]}, DOI={10.1007/s002940050423}, abstractNote={The Cercospora nicotianae SOR1 gene is required for resistance to singlet oxygen-generating photosensitizers. SOR1 was characterized in the wild-type and in five photosensitizer-sensitive mutant strains which are complemented to photosensitizer resistance by transformation with SOR1. Sequence analysis determined that three of the mutants contain SOR1 copies with mutations encoding substitutions in the protein-coding sequence; however, two other mutants had wild-type SOR1 protein and promoter sequences. All five mutants accumulate SOR1 mRNA at levels comparable to that of the wild-type strain. In the wild-type strain, SOR1 accumulation is enhanced two-fold by light, but is unaffected by the presence of cercosporin, the photosensitizer synthesized by C. nicotianae. Southern analysis indicates that SOR1 is present in other fungi that synthesize structurally related perylenequinone photosensitizers.}, number={6}, journal={CURRENT GENETICS}, author={Ehrenshaft, M and Chung, KR and Jenns, AE and Daub, ME}, year={1999}, month={Jan}, pages={478–485} }
 @article{daub_ehrenshaft_jenns_chung_1998, title={Active oxygen in fungal pathogenesis of plants: the role of cercosporin in Cercospora diseases}, volume={32}, number={1998}, journal={Recent Advances in Phytochemistry}, author={Daub, M. E. and Ehrenshaft, M. and Jenns, A. E. and Chung, K. R.}, year={1998}, pages={31–56} }
 @article{ehrenshaft_jenns_chung_daub_1998, title={SOR1, a gene required for photosensitizer and singlet oxygen resistance in Cercospora fungi, is highly conserved in divergent organisms}, volume={1}, ISSN={["1097-2765"]}, DOI={10.1016/S1097-2765(00)80060-X}, abstractNote={Filamentous Cercospora fungi are resistant to photosensitizing compounds that generate singlet oxygen. C. nicotianae photosensitizer-sensitive mutants were restored to full resistance by transformation with SOR1 (Singlet Oxygen Resistance 1), a gene recovered from a wild-type genomic library. SOR1 null mutants generated via targeted gene replacement confirmed the requirement for SOR1 in photosensitizer resistance. SOR1 RNA is present throughout the growth cycle. Although resistance to singlet oxygen is rare in biological systems, SOR1, a gene with demonstrated activity against singlet-oxygen-generating photosensitizers, is highly conserved in organisms from widely diverse taxa. The characterization of SOR1 provides an additional phenotype to this large group of evolutionarily conserved genes.}, number={4}, journal={MOLECULAR CELL}, author={Ehrenshaft, M and Jenns, AE and Chung, KR and Daub, ME}, year={1998}, month={Mar}, pages={603–609} }