Works (5)

Updated: August 1st, 2023 21:15

2019 journal article

Towards microbe-targeted photosensitizers: Synthesis, characterization and in vitro photodynamic inactivation of the tuberculosis model pathogen M. smegmatis by porphyrin-peptide conjugates

Journal of Porphyrins and Phthalocyanines, 23(11n12), 1414–1439.

By: E. Feese n, H. Gracz n, P. Boyle n & R. Ghiladi n

author keywords: antimicrobial; Mycobacterium smegmatis; peptide; photodynamic inactivation; porphyrin; tuberculosis
TL;DR: The ability of PPCs to maintain their antimicrobial photodynamic inactivation efficacy when possessing a short cationic peptides for enabling the potential targeting of pathogens in vivo is demonstrated. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 10, 2020

2012 article

Porphyrin-Cellulose Nanocrystals: A Photobactericidal Material that Exhibits Broad Spectrum Antimicrobial Activity (vol 88, pg 495, 2012)

PHOTOCHEMISTRY AND PHOTOBIOLOGY, Vol. 88, pp. 1034–1034.

Contributors: B. Carpenter n, E. Feese n, H. Sadeghifar n, D. Argyropoulos n & R. Ghiladi n

Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Porphyrin-Cellulose Nanocrystals: A Photobactericidal Material that Exhibits Broad Spectrum Antimicrobial Activity†

Photochemistry and Photobiology, 88(3), 527–536.

By: B. Carpenter n, E. Feese n, H. Sadeghifar n, D. Argyropoulos n & R. Ghiladi n

Contributors: B. Carpenter n, E. Feese n, H. Sadeghifar n, D. Argyropoulos n & R. Ghiladi n

MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Cellulose / chemistry; Drug Resistance, Microbial; Microscopy, Confocal; Microscopy, Fluorescence; Nanoparticles; Photochemotherapy; Porphyrins / chemistry; Spectrophotometry, Ultraviolet; Staphylococcus aureus / drug effects
TL;DR: Research into alternative materials such as CNC‐Por may lead to their application in hospitals and healthcare‐related industries wherein novel materials with the capability of reducing the rates of transmission of a wide range of bacteria, particularly antibiotic resistant strains, are desired. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2011 journal article

Photobactericidal Porphyrin-Cellulose Nanocrystals: Synthesis, Characterization, and Antimicrobial Properties

Biomacromolecules, 12(10), 3528–3539.

By: E. Feese n, H. Sadeghifar*, H. Gracz*, D. Argyropoulos* & R. Ghiladi*

Contributors: E. Feese n, H. Sadeghifar*, H. Gracz*, D. Argyropoulos* & R. Ghiladi*

MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Azides / chemistry; Cellulose / chemistry; Click Chemistry / methods; Disinfectants / chemical synthesis; Disinfectants / pharmacology; Escherichia coli / drug effects; Escherichia coli / growth & development; Escherichia coli / radiation effects; Humans; Light; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microbial Viability / drug effects; Microbial Viability / radiation effects; Molecular Structure; Mycobacterium smegmatis / drug effects; Mycobacterium smegmatis / growth & development; Mycobacterium smegmatis / radiation effects; Nanoparticles / chemistry; Nanotechnology / methods; Photosensitizing Agents / chemical synthesis; Photosensitizing Agents / pharmacology; Porphyrins / chemistry; Species Specificity; Staphylococcus aureus / drug effects; Staphylococcus aureus / growth & development; Staphylococcus aureus / radiation effects; Thermogravimetry
TL;DR: The synthesis, properties, and activity of CNC-Por (5) described herein serve as a benchmark toward the overall objectives of developing novel, potent, bioactive, photobactericidal materials that are effective against a range of bacteria, with potential utilization in the health care and food preparation industries. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Highly efficient in vitro photodynamic inactivation of Mycobacterium smegmatis

Journal of Antimicrobial Chemotherapy, 64(4), 782–785.

By: E. Feese n & R. Ghiladi n

Contributors: E. Feese n & R. Ghiladi n

author keywords: multidrug resistant; TB; photosensitizers
MeSH headings : Colony Count, Microbial; Light; Microbial Viability / radiation effects; Mycobacterium smegmatis / radiation effects; Photosensitizing Agents / pharmacology
TL;DR: The best results demonstrate that PDI of M. smegmatis can achieve a noteworthy 5-6 log unit reduction in cfu (99.999% + viable cell eradication) when cationic PSs are employed in the nanomolar concentration range. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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