Christine L. Merrill

Works (4)

Updated: July 5th, 2023 16:03

2002 journal article

Etomoxir-induced oxidative stress in HepG2 cells detected by differential gene expression is confirmed biochemically

TOXICOLOGICAL SCIENCES, 68(1), 93–101.

By: C. Merrill n, H. Ni, L. Yoon, M. Tirmenstein, P. Narayanan, G. Benavides, M. Easton, D. Creech ...

author keywords: etomoxir; toxicity; oxirane-carboxylates; oxidative stress; gene expression
MeSH headings : Carcinoma, Hepatocellular; Cell Survival / drug effects; DNA / analysis; Dose-Response Relationship, Drug; Enzymes / genetics; Enzymes / metabolism; Epoxy Compounds / toxicity; Gene Expression Regulation; Glutathione / analogs & derivatives; Glutathione / genetics; Glutathione / metabolism; Hepatocytes / drug effects; Hepatocytes / metabolism; Hepatocytes / pathology; Humans; Hypoglycemic Agents / toxicity; Oligonucleotide Array Sequence Analysis; Oxidative Stress / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase / genetics; Thioredoxin-Disulfide Reductase / metabolism; Tumor Cells, Cultured
TL;DR: Etomoxir-induced oxidative stress and impaired mitochondrial energy metabolism were confirmed by a significant decrease in reduced glutathione (GSH), reduced/oxidized glutATHione ratio (G SH/GSSG), mitochondrial membrane potential (MMP), and ATP levels, and by concurrent increase in oxidized glutathion (G SSG) and superoxide generation. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2001 journal article

Teratoma in desert grassland whiptail lizards (Cnemidophorus uniparens)

Journal of Zoo and Wildlife Medicine, 32(2), 257–259.

By: M. Tocidlowski, C. Merrill, M. Loomis & J. Wright

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Osteosarcoma at the site of bone infarction associated with total hip arthroplasty in a dog

VETERINARY SURGERY, 28(1), 54–60.

By: D. Marcellin-Little n, D. DeYoung n, D. Thrall n & C. Merrill n

MeSH headings : Animals; Arthroplasty, Replacement, Hip / adverse effects; Arthroplasty, Replacement, Hip / veterinary; Dog Diseases / etiology; Dogs; Femoral Neoplasms / etiology; Femoral Neoplasms / veterinary; Femur / blood supply; Infarction / complications; Infarction / etiology; Infarction / veterinary; Male; Osteosarcoma / etiology; Osteosarcoma / veterinary
TL;DR: Bilateral medullary bone infarction was visible in the femoral canals 1 year after THA and remained visible on subsequent evaluations, and an osteosarcoma developed in the right distal femoral metaphysis at the site ofinfarction, 5 years after ThA and was found to have metastasized widely throughout the body. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1998 journal article

Axillary cystadenocarcinoma in a Moluccan cockatoo (Cacatua moluccensis)

AVIAN DISEASES, 42(2), 408–412.

By: L. Powers*, C. Merrill*, L. Degernes*, R. Miller*, K. Latimer & H. Barnes*

author keywords: Cacatua moluccensis; cystadenocarcinoma; humerus; Moluccan cockatoo; neoplasia; respiratory
TL;DR: Findings suggest a respiratory neoplasm in the right axillary region of the Moluccan cockatoo, although the tissue of origin remained undetermined. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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