Christine L. Merrill

Works (4)

Updated: July 5th, 2023 16:03

2002 journal article

Etomoxir-induced oxidative stress in HepG2 cells detected by differential gene expression is confirmed biochemically

TOXICOLOGICAL SCIENCES, 68(1), 93–101.

By: C. Merrill n, H. Ni, L. Yoon, M. Tirmenstein, P. Narayanan, G. Benavides, M. Easton, D. Creech ...

author keywords: etomoxir; toxicity; oxirane-carboxylates; oxidative stress; gene expression
MeSH headings : Carcinoma, Hepatocellular; Cell Survival / drug effects; DNA / analysis; Dose-Response Relationship, Drug; Enzymes / genetics; Enzymes / metabolism; Epoxy Compounds / toxicity; Gene Expression Regulation; Glutathione / analogs & derivatives; Glutathione / genetics; Glutathione / metabolism; Hepatocytes / drug effects; Hepatocytes / metabolism; Hepatocytes / pathology; Humans; Hypoglycemic Agents / toxicity; Oligonucleotide Array Sequence Analysis; Oxidative Stress / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Thioredoxin Reductase 1; Thioredoxin-Disulfide Reductase / genetics; Thioredoxin-Disulfide Reductase / metabolism; Tumor Cells, Cultured
TL;DR: Etomoxir-induced oxidative stress and impaired mitochondrial energy metabolism were confirmed by a significant decrease in reduced glutathione (GSH), reduced/oxidized glutATHione ratio (G SH/GSSG), mitochondrial membrane potential (MMP), and ATP levels, and by concurrent increase in oxidized glutathion (G SSG) and superoxide generation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Teratoma in desert grassland whiptail lizards (Cnemidophorus uniparens)

Journal of Zoo and Wildlife Medicine, 32(2), 257–259.

By: M. Tocidlowski, C. Merrill, M. Loomis & J. Wright

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Osteosarcoma at the site of bone infarction associated with total hip arthroplasty in a dog

VETERINARY SURGERY, 28(1), 54–60.

By: D. Marcellin-Little n, D. DeYoung n, D. Thrall n & C. Merrill n

MeSH headings : Animals; Arthroplasty, Replacement, Hip / adverse effects; Arthroplasty, Replacement, Hip / veterinary; Dog Diseases / etiology; Dogs; Femoral Neoplasms / etiology; Femoral Neoplasms / veterinary; Femur / blood supply; Infarction / complications; Infarction / etiology; Infarction / veterinary; Male; Osteosarcoma / etiology; Osteosarcoma / veterinary
TL;DR: Bilateral medullary bone infarction was visible in the femoral canals 1 year after THA and remained visible on subsequent evaluations, and an osteosarcoma developed in the right distal femoral metaphysis at the site ofinfarction, 5 years after ThA and was found to have metastasized widely throughout the body. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Axillary cystadenocarcinoma in a Moluccan cockatoo (Cacatua moluccensis)

AVIAN DISEASES, 42(2), 408–412.

By: L. Powers*, C. Merrill*, L. Degernes*, R. Miller*, K. Latimer & H. Barnes*

author keywords: Cacatua moluccensis; cystadenocarcinoma; humerus; Moluccan cockatoo; neoplasia; respiratory
TL;DR: Findings suggest a respiratory neoplasm in the right axillary region of the Moluccan cockatoo, although the tissue of origin remained undetermined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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