Lisa Jeanne Bain

Works (6)

Updated: July 5th, 2023 16:04

2020 article

20th Pollutant Responses in Marine Organisms (PRIMO 20): Global issues and fundamental mechanisms caused by pollutant stress in marine and freshwater organisms

Baldwin, W. S., Bain, L. J., Giulio, R. D., Kullman, S., Rice, C. D., Ringwood, A. H., & Hurk, P. (2020, September 6). Aquatic Toxicology.

By: W. Baldwin*, L. Bain*, R. Giulio *, S. Kullman n , C. Rice *, A. Ringwood *, P. Hurk *

MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / physiology; Ecosystem; Endocrine Disruptors; Environmental Monitoring; Environmental Pollutants / pharmacology; Fishes; Fresh Water; Humans; Plastics; Water Pollutants, Chemical / toxicity
topics (OpenAlex): Microplastics and Plastic Pollution; Pharmaceutical and Antibiotic Environmental Impacts; Effects and risks of endocrine disrupting chemicals
TL;DR: This issue of Aquatic Toxicology describes the appropriateness of using aquatic organisms as models for human health, while the keynote speakers presented research that highlighted bioaccumulation of contaminants such as PFOS and mercury from fish to marine mammals and coastal human populations such as the Gullah/GeeChee near Charleston, South Carolina, USA. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: October 19, 2020

1997 article

Chronic Toxicity of Environmental Contaminants: Sentinels and Biomarkers

LeBlanc, G. A., & Bain, L. J. (1997, February 1). Environmental Health Perspectives, Vol. 105, pp. 65–80.

By: G. LeBlanc n  & L. Bain n

topics (OpenAlex): Toxic Organic Pollutants Impact
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1997 article

Pesticides: multiple mechanisms of demasculinization

LeBlanc, G. A., Bain, L. J., & Wilson, V. S. (1997, January 1). Molecular and Cellular Endocrinology, Vol. 126, pp. 1–5.

By: G. LeBlanc* , L. Bain n & V. Wilson  n

author keywords: pesticides; demasculinization; feminization; endocrine; steroid hormones; receptors; biotransformation; synergism
MeSH headings : Androgen Antagonists / pharmacology; Androgen Receptor Antagonists; Animals; Female; Feminization / chemically induced; Genitalia, Male / drug effects; Genitalia, Male / growth & development; Humans; Male; Pesticides / pharmacology; Receptors, Estrogen / drug effects
topics (OpenAlex): Effects and risks of endocrine disrupting chemicals; Genetically Modified Organisms Research; Sperm and Testicular Function
TL;DR: Given the ubiquity of pesticides in the environment and the multiple mechanisms whereby they can elicit demasculinizing effects, synergy between such compounds may produce clinical endocrine dysfunction at current human exposure levels. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 article

Structure-Activity Relationships for Xenobiotic Transport Substrates and Inhibitory Ligands of P-Glycoprotein

Bain, L. J., McLachlan, J. B., & LeBlanc, G. A. (1997, August 1). Environmental Health Perspectives, Vol. 105, pp. 812–818.

By: L. Bain n, J. McLachlan  n & G. LeBlanc n 

author keywords: multidrug resistance; multixenobiotic resistance; pesticides; P-glycoprotein; structure-activity relationships
topics (OpenAlex): Drug Transport and Resistance Mechanisms; Computational Drug Discovery Methods; Pesticide and Herbicide Environmental Studies
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6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1996 journal article

Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein

Toxicology and Applied Pharmacology, 141(1), 288.

By: L. Bain & G. LeBlanc

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Mobilization of Pentachlorophenol by GlutathioneS-Transferase μ Increases Cellular Toxicity

Pesticide Biochemistry and Physiology, 54(1), 65–72.

By: L. Bain n & G. LeBlanc n 

topics (OpenAlex): Glutathione Transferases and Polymorphisms; Environmental Toxicology and Ecotoxicology
TL;DR: It is suggested that GST μ may increase the cellular toxicity of PCP by mobilizing this lipophilic compound within the cell by acting to make PCP more bioavailable to elicit toxicity. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

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