Lisa Jeanne Bain

Works (6)

Updated: July 5th, 2023 16:04

2020 article

20th Pollutant Responses in Marine Organisms (PRIMO 20): Global issues and fundamental mechanisms caused by pollutant stress in marine and freshwater organisms

Baldwin, W. S., Bain, L. J., Di Giulio, R., Kullman, S., Rice, C. D., Ringwood, A. H., & Hurk, P. (2020, October). AQUATIC TOXICOLOGY, Vol. 227.

By: W. Baldwin*, L. Bain*, R. Di Giulio *, S. Kullman n , C. Rice *, A. Ringwood *, P. Hurk *

MeSH headings : Animals; Aquatic Organisms / drug effects; Aquatic Organisms / physiology; Ecosystem; Endocrine Disruptors; Environmental Monitoring; Environmental Pollutants / pharmacology; Fishes; Fresh Water; Humans; Plastics; Water Pollutants, Chemical / toxicity
TL;DR: This issue of Aquatic Toxicology describes the appropriateness of using aquatic organisms as models for human health, while the keynote speakers presented research that highlighted bioaccumulation of contaminants such as PFOS and mercury from fish to marine mammals and coastal human populations such as the Gullah/GeeChee near Charleston, South Carolina, USA. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 19, 2020

1997 journal article

At the cutting edge - Pesticides: Multiple mechanisms of demasculinization

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 126(1), 1–5.

By: G. LeBlanc n , L. Bain n & V. Wilson  n

author keywords: pesticides; demasculinization; feminization; endocrine; steroid hormones; receptors; biotransformation; synergism
MeSH headings : Androgen Antagonists / pharmacology; Androgen Receptor Antagonists; Animals; Female; Feminization / chemically induced; Genitalia, Male / drug effects; Genitalia, Male / growth & development; Humans; Male; Pesticides / pharmacology; Receptors, Estrogen / drug effects
TL;DR: Given the ubiquity of pesticides in the environment and the multiple mechanisms whereby they can elicit demasculinizing effects, synergy between such compounds may produce clinical endocrine dysfunction at current human exposure levels. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

Chronic toxicity of environmental contaminants: Sentinels and biomarkers

Environmental Health Perspectives, 105(Suppl. 1), 65–80.

By: G. LeBlanc n  & L. Bain n

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1997 journal article

Structure-activity relationships for xenobiotic transport substrates and inhibitory ligands of P-glycoprotein

ENVIRONMENTAL HEALTH PERSPECTIVES, 105(8), 812–818.

By: L. Bain n, J. McLachlan  n & G. LeBlanc n 

author keywords: multidrug resistance; multixenobiotic resistance; pesticides; P-glycoprotein; structure-activity relationships
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1996 journal article

Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein

Toxicology and Applied Pharmacology, 141(1), 288.

By: L. Bain & G. LeBlanc

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Mobilization of Pentachlorophenol by GlutathioneS-Transferase μ Increases Cellular Toxicity

Pesticide Biochemistry and Physiology, 54(1), 65–72.

By: L. Bain n & G. LeBlanc n 

TL;DR: It is suggested that GST μ may increase the cellular toxicity of PCP by mobilizing this lipophilic compound within the cell by acting to make PCP more bioavailable to elicit toxicity. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

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