Works (14)

Updated: July 5th, 2023 16:02

2004 journal article

Comparison of storage methods for reverse-transcriptase PCR amplification of rotavirus RNA from gorilla (Gorilla g. gorilla) fecal samples

Journal of Virological Methods, 116(1), 17-.

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Comparison of the cardiorespiratory effects of medetomidine- butorphanol-ketamine and medetomidine-butorphanol-midazolam in patas monkeys (Erythrocebus patas)

Journal of Zoo and Wildlife Medicine, 34(1), 47–52.

By: G. Kalema-Zikusoka, W. Horne, J. Levine & M. Loomis

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Comparison of the efficacy and cardiorespiratory effects of medetomidine-based anesthetic protocols in ring-tailed lemurs (Lemur catta)

Journal of Zoo and Wildlife Medicine, 34(2), 163–170.

By: C. Williams, K. Glenn, J. Levine & W. Horne

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Alternative splicing of a beta(4) subunit proline-rich motif regulates voltage-dependent gating and toxin block of Ca(v)2.1 Ca2+ channels

Journal of Neuroscience, 22(21), 9331–9339.

By: T. Helton*, D. Kojetin n, J. Cavanagh n & W. Horne*

MeSH headings : Alternative Splicing / physiology; Amino Acid Motifs / physiology; Animals; Brain / metabolism; Calcium Channel Blockers / pharmacology; Calcium Channels, N-Type / drug effects; Calcium Channels, N-Type / genetics; Calcium Channels, N-Type / metabolism; Humans; Ion Channel Gating / drug effects; Ion Channel Gating / physiology; Membrane Potentials / physiology; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins / genetics; Oocytes / metabolism; Organ Specificity; Patch-Clamp Techniques; Protein Structure, Tertiary / physiology; Protein Subunits / drug effects; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Messenger / metabolism; Sequence Deletion; Sequence Homology, Amino Acid; Spinal Cord / metabolism; Structure-Activity Relationship; Xenopus laevis; omega-Conotoxins / pharmacology
TL;DR: The models reveal that alternative splicing of the β4 N terminus results in dramatic differences in surface charge distribution and localize the proline-rich motif of β4b to an extended arm structure that flanks what would be the equivalent of a highly modified PSD-95 carboxylate binding loop. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Alternative splicing of the beta(4) subunit has alpha(1) subunit subtype-specific effects on Ca2+ channel gating

Journal of Neuroscience, 22(5), 1573–1582.

By: T. Helton & W. Horne

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Cardiorespiratory effects of medetomidine-butorphanol, medetomidine-butorphanol-diazepam, and medetomidine-butorphanol-ketamine in captive red wolves (Canis rufus).

Journal of Zoo and Wildlife Medicine, 33(2), 101–107.

Source: NC State University Libraries
Added: August 6, 2018

2002 article

Medetomidine, ketamine, and sevoflurane for anesthesia for injured loggerhead sea turtles: 13 cases (1996-2000)

Chittick, E. J., Stamper, M. A., Beasley, J. F., Lewbart, G. A., & Horne, W. A. (2002, October 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 221, pp. 1019–1025.

By: E. Chittick n, M. Stamper*, J. Beasley, G. Lewbart n & W. Horne n

MeSH headings : Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Blood Gas Analysis / veterinary; Dose-Response Relationship, Drug; Female; Heart Rate / drug effects; Hypnotics and Sedatives; Ketamine; Male; Medetomidine; Methyl Ethers; Partial Pressure; Retrospective Studies; Safety; Sevoflurane; Time Factors; Treatment Outcome; Turtles / injuries; Turtles / physiology
TL;DR: Results suggest that a combination of medetomidine and ketamine for induction and sevoflurane for maintenance provides safe, effective, controllable anesthesia in injured loggerhead sea turtles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

A simple method of providing intermittent positive-pressure ventilation to etorphine-immobilized elephants (Loxodonta africana) in the field

Journal of Zoo and Wildlife Medicine, 32(4), 519–522.

By: W. Horne, M. Tchamba & M. Loomis

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Cardiopulmonary assessment of medetomidine, ketamine, and butorphanol anesthesia in captive Thomson's gazelles (Gazella thomsoni)

Journal of Zoo and Wildlife Medicine, 32(2), 168–175.

By: E. Chittick, W. Horne, B. Wolfe, K. Sladky & M. Loomis

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

C-terminal alternative splicing changes the gating properties of a human spinal cord calcium channel alpha 1A subunit

Journal of Neuroscience, 20(20), 7564–7570.

By: H. Krovetz n, T. Helton n, A. Crews n & W. Horne n

MeSH headings : Alternative Splicing; Amino Acid Substitution; Animals; Calcium Channels / genetics; Calcium Channels / metabolism; Cells, Cultured; Cerebellum / metabolism; Exons; Gene Expression; Humans; Ion Channel Gating / genetics; Membrane Potentials / physiology; Microinjections; Molecular Sequence Data; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Oocytes / metabolism; Patch-Clamp Techniques; Protein Isoforms / genetics; Protein Isoforms / metabolism; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Spinal Cord / metabolism; Xenopus
TL;DR: It is demonstrated that C-terminal structural changes alone can influence the way in which α1A subunits respond to a depolarizing stimulus and add to the developing picture of the C terminus as a critical domain in the regulation of Ca2+ channel function. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2000 article

Cardiorespiratory effects of four alpha(2)-adrenoceptor agonist-ketamine combinations in captive red wolves

Sladky, K. K., Kelly, B. T., Loomis, M. R., Stoskopf, M. K., & Horne, W. A. (2000, November 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 217, pp. 1366–1371.

By: K. Sladky n, B. Kelly n, M. Loomis n, M. Stoskopf n & W. Horne n

MeSH headings : Acepromazine / pharmacology; Adrenergic alpha-Agonists / pharmacology; Analgesics, Opioid / pharmacology; Anesthetics, Dissociative / pharmacology; Animals; Blood Gas Analysis; Blood Pressure / drug effects; Body Temperature; Butorphanol / pharmacology; Conservation of Natural Resources; Electrocardiography / veterinary; Female; Heart Rate / drug effects; Ketamine / pharmacology; Male; Medetomidine / pharmacology; Oximetry / veterinary; Prospective Studies; Respiration / drug effects; Wolves / physiology; Xylazine / pharmacology
TL;DR: The alpha2-adrenoceptor agonist-ketamine combinations provide rapid reversible anesthesia for red wolves but cause severe sustained hypertension, which puts animals at risk for development of cerebral encephalopathy, retinal hemorrhage, pulmonary edema, and myocardial failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Cloning and sequencing hybrid striped bass (Morone saxatilis x M. chrysops) transforming growth factor-β (TGF-β), and development of a reverse transcription quantitative competitive polymerase chain reaction (RT-qcPCR) assay to measure TGF-β mRNA of teleost fish

Fish & Shellfish Immunology, 10(1), 61–85.

By: C. Harms n, S. Kennedy-Stoskopf n, W. Horne n, F. Fuller n & W. Tompkins n

author keywords: transforming growth factor-beta; TGF-beta; sequence; hybrid striped bass; Morone saxatilis X M-chrysops; quantitative PCR
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Bass / metabolism; Blotting, Northern / veterinary; Blotting, Southern / veterinary; Chimera / genetics; Cloning, Molecular; Consensus Sequence; Humans; Kidney / chemistry; Molecular Sequence Data; Oncorhynchus mykiss; RNA, Messenger / analysis; Rats; Reverse Transcriptase Polymerase Chain Reaction / methods; Transforming Growth Factor beta / genetics; Xenopus
TL;DR: Higher levels of TGF-beta mRNA expression were detected in mononuclear cells of peripheral blood than from spleen or anterior kidney, and a reverse transcription quantitative competitive polymerase chain reaction (RT-qcPCR) assay was devised to measure T GF- beta mRNA expression in teleost fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2000 journal article

Evaluation of epidural morphine for postoperative analgesia in ferrets (Mustela putorius furo)

Contemporary Topics in Laboratory Animal Science, 39(6), 33–38.

By: K. Sladky, W. Horne, K. Goodrowe, M. Stoskopf, M. Loomis & C. Harms

Source: NC State University Libraries
Added: August 6, 2018

journal article

Epidural analgesia in ferrets

Harms, C. A., Sladky, K. K., Horne, W. A., & Stoskopf, M. K. Exotic DVM, 4(3), 40–42.

By: C. Harms, K. Sladky, W. Horne & M. Stoskopf

Source: NC State University Libraries
Added: August 6, 2018

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