@article{sela_rawsthorne_mills_2007, title={Characterization of the lactococcal group II intron target site in its native host}, volume={58}, ISSN={["1095-9890"]}, DOI={10.1016/j.plasmid.2007.02.003}, abstractNote={The Lactococcus lactis group II intron (Ll.ltrB) retrohomes into the ltrB gene at high efficiency. To date, the critical DNA bases recognized in vivo by the Ll.ltrB ribonucleoprotein (RNP) have been exclusively elucidated in Escherichia coli. However, recent evidence indicates host-dependant differences in Ll.ltrB mobility, raising the possibility of limitations of the current model for RNP-homing site recognition in the native L. lactis host. In this work, intron retargeting experiments in L. lactis have demonstrated that adherence to specific target site critical bases is not sufficient to predict success or failure of chromosomal invasion, as in E. coli. Accordingly, a quantitative real-time PCR (QPCR) assay was developed to test target site nucleotides previously demonstrated as critical for homing in E. coli, for relevance in its native host. This two-plasmid QPCR homing assay is highly sensitive and, unlike previous E. coli-based assays, resolves differential homing efficiencies in the absence of selection. As in E. coli, deviation from wild type at target site positions −23, −21, −20, −19, and +5 resulted in lower homing efficiencies in L. lactis. Furthermore, the same trends are observed when assaying select variants in Enterococcus faecalis. Our results suggest that these target site positions are critical in both E. coli and L. lactis.}, number={2}, journal={PLASMID}, author={Sela, David A. and Rawsthorne, Helen and Mills, David A.}, year={2007}, month={Sep}, pages={127–139} }
 @article{madsen_mills_djordjevic_israelsen_klaenhammer_2001, title={Analysis of the genetic switch and replication region of a P335-type bacteriophage with an obligate lytic lifestyle on Lactococcus lactis}, volume={67}, ISSN={["1098-5336"]}, DOI={10.1128/AEM.67.3.1128-1139.2001}, abstractNote={ABSTRACT}, number={3}, journal={APPLIED AND ENVIRONMENTAL MICROBIOLOGY}, author={Madsen, SM and Mills, D and Djordjevic, G and Israelsen, H and Klaenhammer, TR}, year={2001}, month={Mar}, pages={1128–1139} }
 @article{mills_phister_dunny_mckay_1998, title={An origin of transfer (oriT) on the conjugative element pRS01 from Lactococcus lactis subsp. lactis ML3}, volume={64}, number={4}, journal={Applied and Environmental Microbiology}, author={Mills, D. A. and Phister, T. G. and Dunny, G. M. and McKay, L. L.}, year={1998}, pages={1541–1544} }