S. Rochelle Mikkelsen

Works (2)

Updated: July 5th, 2023 15:48

2011 article

Partial Regulatory T Cell Depletion Prior to Acute Feline Immunodeficiency Virus Infection Does Not Alter Disease Pathogenesis

Mikkelsen, S. R., Long, J. M., Zhang, L., Galemore, E. R., VandeWoude, S., & Dean, G. A. (2011, February 25). PLoS ONE.

By: S. Mikkelsen n, J. Long  n, L. Zhang n, E. Galemore n, S. VandeWoude * & G. Dean n

MeSH headings : Acute Disease; Acute-Phase Reaction / immunology; Animals; Antibodies, Monoclonal / administration & dosage; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; Cat Diseases / immunology; Cat Diseases / virology; Cats; Disease Progression; Down-Regulation / immunology; Feline Acquired Immunodeficiency Syndrome / etiology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / pathology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / physiology; Interleukin-2 Receptor alpha Subunit / immunology; Lymphocyte Count; Lymphocyte Depletion / methods; Lymphocyte Depletion / veterinary; Specific Pathogen-Free Organisms; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Viremia / veterinary
topics (OpenAlex): HIV Research and Treatment; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: It is reported here that partial Treg cell depletion prior to FIV infection does not significantly change provirus, viremia, or CD4+ T cell levels in blood and lymphoid tissues during the acute phase of disease. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 article

In vivo depletion of CD4+CD25hi regulatory T cells is associated with improved antiviral responses in cats chronically infected with feline immunodeficiency virus

Mikkelsen, S. R., Reckling, S. K., Egan, E. A., & Dean, G. A. (2010, May 17). Virology.

By: S. Mikkelsen n, S. Reckling n, E. Egan n & G. Dean n

author keywords: Feline immunodeficiency virus; HIV-1; Lentivirus; Regulatory T cell; Immunosuppression; Monoclonal antibody
MeSH headings : Animals; Antibodies, Monoclonal / administration & dosage; Antibodies, Viral / blood; CD4 Antigens / analysis; Cat Diseases / immunology; Cat Diseases / virology; Cats; Female; Immunodeficiency Virus, Feline / immunology; Interleukin-2 Receptor alpha Subunit / analysis; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Depletion; T-Lymphocytes, Regulatory / chemistry; T-Lymphocytes, Regulatory / immunology
topics (OpenAlex): HIV Research and Treatment; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: It is proposed that short-term in vivo Treg cell depletion during chronic HIV-1 infection could provide a window of opportunity for therapeutic vaccination in individuals with controlled viral replication. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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