2000 journal article

The ferritin iron entry and exit problem

INORGANICA CHIMICA ACTA, 297(1-2), 242–251.

By: E. Theil*, H. Takagi n, G. Small n, L. He n, A. Tipton & D. Danger n

author keywords: ferritin; iron biominerals; ferroxidation; iron/dioxygen catalysis
TL;DR: The entry and exit of Fe(II) ions in ferritin are endpoints in the process which concentrates iron as a solid (hydrated ferric oxide) to be used by living cells, suggesting a regulation-sensitive biological signal for iron exit. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Crystal structure of bullfrog M ferritin at 2.8 angstrom resolution: analysis of subunit interactions and the binuclear metal center


By: Y. Ha*, D. Shi*, G. Small n, E. Theil n & N. Allewell*

author keywords: crystallography; iron oxidation; iron storage; multisubunit proteins
MeSH headings : Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Ferritins / chemistry; Ferritins / metabolism; Magnesium / metabolism; Models, Molecular; Molecular Sequence Data; Protein Conformation; Rana catesbeiana; Sequence Homology, Amino Acid; Tyrosine / analysis; Tyrosine / metabolism
TL;DR: The crystal structure of the homopolymer of recombinant frog M ferritin is determined and it is suggested that Gln137 and Asp140 are a vestige of the second GluxxHis site, resulting from single nucleotide mutations of Glu and His codons and giving rise to Ala140 or Ser140 present in other eukaryotic H-type ferritins, by additional singleucleotide mutations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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