Ganokon Urkasemsin

Works (6)

Updated: July 24th, 2023 21:15

2017 journal article

Genetics of Hereditary Ataxia in Scottish Terriers

Journal of Veterinary Internal Medicine, 31(4), 1132–1139.

By: G. Urkasemsin n, D. Nielsen n , A. Singleton *, S. Arepalli*, D. Hernandez *, C. Agler  n, N. Olby n 

author keywords: Canine; Cerebellar abiotrophy; Cerebellar ataxia; Neurodegeneration
MeSH headings : Animals; Brain / diagnostic imaging; Dog Diseases / diagnostic imaging; Dog Diseases / genetics; Dogs; Female; Genetic Linkage / genetics; Genome-Wide Association Study / veterinary; Homozygote; Magnetic Resonance Imaging / veterinary; Male; Neuroimaging / veterinary; Pedigree; Spinocerebellar Degenerations / diagnostic imaging; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / veterinary
TL;DR: This finding suggests that further genetic investigation of the potential region of interest on CFA X should be considered in order to identify the causal mutation as well as develop a genetic test to eliminate the disease from this breed. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Clinical characteristics of Scottie Cramp in 31 cases

Journal of Small Animal Practice, 56(4), 276–280.

By: G. Urkasemsin n & N. Olby n 

MeSH headings : Animals; Breeding; Cerebellum / pathology; Dog Diseases / drug therapy; Dog Diseases / genetics; Dog Diseases / physiopathology; Dogs; Female; Fluoxetine / therapeutic use; Genetic Predisposition to Disease; Male; Muscle Cramp / drug therapy; Muscle Cramp / genetics; Muscle Cramp / physiopathology; Muscle Cramp / veterinary; Muscle Hypertonia / drug therapy; Muscle Hypertonia / genetics; Muscle Hypertonia / physiopathology; Muscle Hypertonia / veterinary; Selective Serotonin Reuptake Inhibitors / therapeutic use; Severity of Illness Index; Sex Factors; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / physiopathology; Spinocerebellar Degenerations / veterinary
TL;DR: The disorder recognised as Scottie Cramp by dog owners includes dogs with hind limb spasticity in addition to generalised cramping, which usually improve over time without specific treatment. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2014 journal article

Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24

PLoS Genetics, 10(2).

By: C. Agler, D. Nielsen , G. Urkasemsin, A. Singleton, N. Tonomura, S. Sigurdsson, R. Tang, K. Linder ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Titanium-enriched hydroxyapatite-gelatin scaffolds with osteogenically differentiated progenitor cell aggregates for calvaria bone regeneration

Tissue Engineering. Part A, 19(15-16), 1803–1816.

By: J. Ferreira, R. Padilla, G. Urkasemsin, K. Yoon, K. Goeckner, W. Hu, C. Ko

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Mapping of Purkinje Neuron Loss and Polyglucosan Body Accumulation in Hereditary Cerebellar Degeneration in Scottish Terriers

VETERINARY PATHOLOGY, 49(5), 852–859.

By: G. Urkasemsin n, K. Linder n, J. Bell*, A. Lahunta* & N. Olby n 

author keywords: dog; cerebellar abiotrophy; cerebellar ataxia; cerebellar cortex; inclusion; molecular layer; polyglucosan body
MeSH headings : Aging / pathology; Animals; Case-Control Studies; Cerebellar Cortex / metabolism; Cerebellar Cortex / pathology; Cerebellar Cortex / ultrastructure; Cerebellum / metabolism; Cerebellum / pathology; Cerebellum / ultrastructure; Dog Diseases / genetics; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Female; Glucans / metabolism; Immunohistochemistry / veterinary; Inclusion Bodies / metabolism; Inclusion Bodies / pathology; Inclusion Bodies / ultrastructure; Male; Microscopy, Electron, Transmission / veterinary; Purkinje Cells / metabolism; Purkinje Cells / pathology; Purkinje Cells / ultrastructure; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / metabolism; Spinocerebellar Degenerations / pathology; Spinocerebellar Degenerations / veterinary
TL;DR: Significant Purkinje cell loss and increased polyglucosan bodies in the cerebellum of affected Scottish Terriers are demonstrated. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2010 journal article

Hereditary Cerebellar Degeneration in Scottish Terriers

JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(3), 565–570.

By: G. Urkasemsin n, K. Linder n, J. Bell*, A. Lahunta* & N. Olby n 

author keywords: Canine; Cerebellar abiotrophy; Cerebellar ataxia; Polyglucosan body; Purkinje cell
MeSH headings : Animals; Cerebellum / pathology; Dog Diseases / genetics; Dogs; Female; Genetic Predisposition to Disease; Male; Pedigree; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / veterinary
TL;DR: A hereditary cerebellar degenerative disorder with a relatively mild phenotype has emerged in the Scottish Terrier and genetic analysis results are consistent with an autosomal recessive mode of inheritance. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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