@article{durham_magwire_stone_leips_2014, title={Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits}, volume={5}, ISSN={["2041-1723"]}, DOI={10.1038/ncomms5338}, abstractNote={Most organisms exhibit senescence; a decline in physiological function with age. In nature, rates of senescence vary extensively among individuals and this variation has a significant genetic component; however, we know little about the genes underlying senescence. Here we show the first evidence that individual alleles influence fecundity in an age-specific manner and so the genetic basis of natural variation in fecundity changes dramatically with age. We complete a genome-wide association to identify single-nucleotide polymorphisms (SNPs) affecting lifespan and age-specific fecundity using the Drosophila melanogaster Genetic Reference Panel. We identify 1,031 SNPs affecting fecundity and 52 influencing lifespan. Only one SNP is associated with both early- and late-age fecundity. The age-specific effect of candidate genes on fecundity is validated using RNA interference. In addition, there is a dramatic increase in the number of SNPs influencing fecundity with age. This result provides support for the mutation accumulation theory of aging.}, journal={NATURE COMMUNICATIONS}, author={Durham, Mary F. and Magwire, Michael M. and Stone, Eric A. and Leips, Jeff}, year={2014}, month={Jul} }
 @article{huang_massouras_inoue_peiffer_ramia_tarone_turlapati_zichner_zhu_lyman_et al._2014, title={Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines}, volume={24}, number={7}, journal={Genome Research}, author={Huang, W. and Massouras, A. and Inoue, Y. and Peiffer, J. and Ramia, M. and Tarone, A. M. and Turlapati, L. and Zichner, T. and Zhu, D. H. and Lyman, R. F. and et al.}, year={2014}, pages={1193–1208} }
 @article{ober_huang_magwire_schlather_simianer_mackay, title={Accounting for genetic architecture improves sequence based genomic prediction for a Drosophila fitness trait}, volume={10}, number={5}, journal={PLoS One}, author={Ober, U. and Huang, W. and Magwire, M. and Schlather, M. and Simianer, H. and Mackay, T. F. C.} }
 @article{zwarts_magwire_carbone_versteven_herteleer_anholt_callaerts_mackay, title={Complex genetic architecture of Drosophila aggressive behavior}, volume={108}, number={41}, journal={Proceedings of the National Academy of Sciences of the United States of America}, author={Zwarts, L. and Magwire, M. M. and Carbone, M. A. and Versteven, M. and Herteleer, L. and Anholt, R. R. H. and Callaerts, P. and Mackay, T. F. C.}, pages={17070–17075} }
 @article{huang_richards_carbone_zhu_anholt_ayroles_duncan_jordan_lawrence_magwire_et al., title={Epistasis dominates the genetic architecture of Drosophila quantitative traits}, volume={109}, number={39}, journal={Proceedings of the National Academy of Sciences of the United States of America}, author={Huang, W. and Richards, S. and Carbone, M. A. and Zhu, D. H. and Anholt, R. R. H. and Ayroles, J. F. and Duncan, L. and Jordan, K. W. and Lawrence, F. and Magwire, M. M. and et al.}, pages={15553–15559} }
 @article{huang_carbone_magwire_peiffer_lyman_stone_anholt_mackay, title={Genetic basis of transcriptome diversity in Drosophila melanogaster}, volume={112}, number={44}, journal={Proceedings of the National Academy of Sciences of the United States of America}, author={Huang, W. and Carbone, M. A. and Magwire, M. M. and Peiffer, J. A. and Lyman, R. F. and Stone, E. A. and Anholt, R. R. H. and Mackay, T. F. C.}, pages={E6010–6019} }
 @article{weber_khan_magwire_tabor_mackay_anholt, title={Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster}, volume={7}, number={4}, journal={PLoS One}, author={Weber, A. L. and Khan, G. F. and Magwire, M. M. and Tabor, C. L. and Mackay, T. F. C. and Anholt, R. R. H.} }
 @article{jordan_craver_magwire_cubilla_mackay_anholt, title={Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster}, volume={7}, number={6}, journal={PLoS One}, author={Jordan, K. W. and Craver, K. L. and Magwire, M. M. and Cubilla, C. E. and Mackay, T. F. C. and Anholt, R. R. H.} }
 @article{ivanov_escott-price_ziehm_magwire_mackay_partridge_thomton, title={Longevity GWAS using the Drosophila Genetic Reference Panel}, volume={70}, number={12}, journal={Journals of Gerontology. Series A, Biological Sciences Medical Sciences}, author={Ivanov, D. K. and Escott-Price, V. and Ziehm, M. and Magwire, M. M. and Mackay, T. F. C. and Partridge, L. and Thomton, J. M.}, pages={1470–1478} }
 @article{arya_weber_wang_magwire_negron_mackay_anholt, title={Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster}, volume={186}, number={4}, journal={Genetics}, author={Arya, G. H. and Weber, A. L. and Wang, P. and Magwire, M. M. and Negron, Y. L. S. and Mackay, T. F. C. and Anholt, R. R. H.}, pages={1475–623} }
 @article{magwire_yamamoto_carbone_roshina_symonenko_pasyukova_morozova_mackay, title={Quantitative and molecular genetic analyses of mutations increasing Drosophila life span}, volume={6}, number={7}, journal={PLoS Genetics}, author={Magwire, M. M. and Yamamoto, A. and Carbone, M. A. and Roshina, N. V. and Symonenko, A. V. and Pasyukova, E. G. and Morozova, T. V. and Mackay, T. F. C.} }
 @article{huang_lyman_lyman_carbone_harbison_magwire_mackay, title={Spontaneous mutations and the origin and maintenance of quantitative genetic variation}, volume={5}, journal={Elife}, author={Huang, W. and Lyman, R. F. and Lyman, R. A. and Carbone, M. A. and Harbison, S. T. and Magwire, M. M. and Mackay, T. F. C.} }
 @article{mackay_richards_stone_barbadilla_ayroles_zhu_casillas_han_magwire_cridland_et al., title={The Drosophila melanogaster genetic reference panel}, volume={482}, number={7384}, journal={Nature}, author={Mackay, T. F. C. and Richards, S. and Stone, E. A. and Barbadilla, A. and Ayroles, J. F. and Zhu, D. H. and Casillas, S. and Han, Y. and Magwire, M. M. and Cridland, J. M. and et al.}, pages={173–178} }
 @article{shorter_geisz_ozsoy_magwire_carbone_mackay, title={The effects of royal jelly on fitness traits and gene expression in Drosophila melanogaster}, volume={10}, number={7}, journal={PLoS One}, author={Shorter, J. R. and Geisz, M. and Ozsoy, E. and Magwire, M. M. and Carbone, M. A. and Mackay, T. F. C.} }
 @article{arya_magwire_huang_serrano-negron_mackay_anholt, title={The genetic basis for variation in olfactory behavior in Drosophila melanogaster}, volume={40}, number={4}, journal={Chemical Senses}, author={Arya, G. H. and Magwire, M. M. and Huang, W. and Serrano-Negron, Y. L. and Mackay, T. F. C. and Anholt, R. R. H.}, pages={233–243} }
 @article{zwarts_vanden broeck_cappuyns_ayroles_magwire_vulsteke_clements_mackay_callaerts, title={The genetic basis of natural variation in mushroom body size in Drosophila melanogaster}, volume={6}, journal={Nature Communications}, author={Zwarts, L. and Vanden Broeck, L. and Cappuyns, E. and Ayroles, J. F. and Magwire, M. M. and Vulsteke, V. and Clements, J. and Mackay, T. F. C. and Callaerts, P.} }