Works (5)

Updated: July 5th, 2023 16:02

2002 journal article

Adsorptive immobilization of cytochrome c on indium/tin oxide (ITO): electrochemical evidence for electron transfer-induced conformational changes

ELECTROCHEMISTRY COMMUNICATIONS, 4(2), 177–181.

By: A. El Kasmi*, M. Leopold n, R. Galligan n, R. Robertson*, S. Saavedra*, K. El Kacemi*, E. Bowden n

author keywords: cytochrome c monolayers; indium/tin oxide; redox-linked conformational changes; interfacial electron transfer kinetics; unusual quasireversibility
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Influence of gold substrate topography on the voltammetry of cytochrome c adsorbed on carboxylic acid terminated self-assembled monolayers

LANGMUIR, 18(6), 2239–2245.

By: M. Leopold n & E. Bowden n

Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Influence of gold topography on carboxylic acid terminated self-assembled monolayers

LANGMUIR, 18(4), 978–980.

By: M. Leopold n, J. Black n & E. Bowden n

Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction

BIOCHEMISTRY, 39(24), 7266–7275.

By: L. Goldstein n, M. Leopold n, X. Huang n, C. Atwood n, A. Saunders n, M. Hartshorn n, J. Lim n, K. Faget n ...

MeSH headings : 3-Hydroxyanthranilic Acid / metabolism; Animals; Ascorbic Acid / metabolism; Cataract / etiology; Cattle; Copper / metabolism; Crystallins / metabolism; Electrochemistry; Humans; Hydrogen Peroxide / metabolism; Iron / metabolism; Kynurenine / analogs & derivatives; Kynurenine / metabolism; Lens, Crystalline / metabolism; Metals / metabolism; Oxidation-Reduction; Superoxides / metabolism; Tryptophan / metabolism
TL;DR: The reaction of kynurenine pathway catabolites with copper and iron, as well as interactions with the major lenticular structural proteins, the alpha-crystallins, support the possibility that 3HK and 3HAA may be cofactors in the oxidative damage of proteins through interactions with redox-active metals and especially copper. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction

JOURNAL OF BIOLOGICAL CHEMISTRY, 274(52), 37111–37116.

By: X. Huang*, M. Cuajungco*, C. Atwood*, M. Hartshorn*, J. Tyndall*, G. Hanson, K. Stokes n, M. Leopold n ...

MeSH headings : Amyloid beta-Peptides / toxicity; Animals; Brain / drug effects; Cells, Cultured; Computer Simulation; Copper / metabolism; Copper / pharmacology; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide / metabolism; Oxidation-Reduction; Rats
TL;DR: It is reported that Cu(II) markedly potentiates the neurotoxicity exhibited by Aβ in cell culture, suggesting that certain redox active metal ions may be important in exacerbating and perhaps facilitating Aβ-mediated oxidative damage in Alzheimer's disease. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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