Susan M. Michalowski

Works (4)

Updated: July 5th, 2023 16:04

2005 journal article

The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling

LIFE SCIENCES, 77(19), 2457–2470.

By: C. Culver n, S. Michalowski n, R. Maia n & S. Laster n

author keywords: apoptosis; NDGA; cPLA(2)
MeSH headings : Animals; Antioxidants / pharmacology; Apoptosis / drug effects; Arachidonic Acid / metabolism; Blotting, Western; Butylated Hydroxyanisole / pharmacology; Calcium Signaling / drug effects; Caspases / metabolism; Cell Line; Chromium Radioisotopes; Enzyme Activation / drug effects; Fibroblasts / drug effects; Fibroblasts / metabolism; Immunoprecipitation; Male; Masoprocol / pharmacology; Mice; Microscopy, Phase-Contrast; Phosphates / metabolism; Phospholipases A / antagonists & inhibitors; Tumor Necrosis Factor-alpha / pharmacology
TL;DR: The mechanism underlying the ability of NDGA to inhibit TNF-induced apoptosis is examined and it is shown that NDGA blocks many key indicators of apoptosis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2001 patent

Matrix attachment regions

Washington, DC: U.S. Patent and Trademark Office.

By: S. Michalowski & S. Spiker

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Characterization of randomly-obtained matrix attachment regions (MARs) from higher plants

BIOCHEMISTRY, 38(39), 12795–12804.

By: S. Michalowski n, G. Allen n, G. Hall n, W. Thompson n  & S. Spiker n

MeSH headings : Base Sequence; Cloning, Molecular; DNA, Plant; Molecular Sequence Data; Nuclear Matrix / metabolism; Plants / metabolism
TL;DR: Binding strength is a function of both numbers of binding sites and affinity for the sites, and a newly identified motif, the "90%AT Box," correlates better with binding strength than any of the previously identified motifs investigated. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1997 journal article

The tomato RBCS3A promoter requires integration into the chromatin for correct organ-specific regulation

FEBS LETTERS, 415(1), 91–95.

By: I. Meier *, B. Groning*, S. Michalowski n & S. Spiker n

author keywords: chromatin; matrix attachment region; organ-specific; RBCS promoter; tomato
MeSH headings : Antigens, Nuclear; Biolistics; Cell Nucleus / metabolism; Chromatin / metabolism; DNA-Binding Proteins / analysis; Gene Expression Regulation, Plant; Genes, Plant / genetics; Genes, Reporter; Solanum lycopersicum / enzymology; Solanum lycopersicum / genetics; Nuclear Proteins / genetics; Nuclear Proteins / metabolism; Plants, Genetically Modified; Plasmids / genetics; Promoter Regions, Genetic / genetics; Protein Binding; Ribulose-Bisphosphate Carboxylase / genetics; Transformation, Genetic
TL;DR: Fruit‐specific repression of the RBCS3A promoter was observed in transgenic plants, but not after ballistic transient transformation, indicating that chromatin integration is necessary for its correct organ‐specific regulation. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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