Guanxi Xiao

Works (3)

Updated: July 5th, 2023 15:47

2017 article

Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells

Beattie, R., Postiglione, M. P., Burnett, L. E., Laukoter, S., Streicher, C., Pauler, F. M., … Hippenmeyer, S. (2017, May 1). Neuron.

By: R. Beattie *, M. Postiglione*, L. Burnett *, S. Laukoter *, C. Streicher*, F. Pauler *, G. Xiao n, O. Klezovitch* ...

MeSH headings : Animals; Cell Polarity; Cell Proliferation / genetics; Embryo, Mammalian / metabolism; Glycoproteins / genetics; Glycoproteins / metabolism; Mice; Mice, Knockout; Microscopy, Confocal; Neocortex / embryology; Neocortex / growth & development; Neocortex / pathology; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / genetics; Neuroglia / cytology; Neuroglia / metabolism; Neurons / cytology; Neurons / metabolism
topics (OpenAlex): Neurogenesis and neuroplasticity mechanisms; RNA Research and Splicing; Single-cell and spatial transcriptomics
TL;DR: Results suggest that NSC-mediated neuron and glia production is tightly regulated through the concerted interplay of sequential Lgl1-dependent global and cell intrinsic mechanisms. (via Semantic Scholar)
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Source: NC State University Libraries
Added: August 6, 2018

2013 article

Neural development is dependent on the function of specificity protein 2 in cell cycle progression

Liang, H., Xiao, G., Yin, H., Hippenmeyer, S., Horowitz, J. M., & Ghashghaei, H. T. (2013, January 4). Development.

By: H. Liang n, G. Xiao n, H. Yin n, S. Hippenmeyer *, J. Horowitz n & H. Ghashghaei n

author keywords: Neurogenesis; Neural stem cells; Neural progenitors; Sp2; Cell cycle; M phase; Mouse
MeSH headings : Animals; Brain / cytology; Brain / embryology; Brain / metabolism; Cell Count; Cell Cycle; Cell Proliferation; Crosses, Genetic; Embryo Implantation; Embryo, Mammalian / cytology; Embryo, Mammalian / metabolism; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Eye Proteins / genetics; Eye Proteins / metabolism; Female; Genetic Markers; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Homologous Recombination; Intermediate Filament Proteins / genetics; Intermediate Filament Proteins / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Nestin; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis; Neurons / cytology; Neurons / metabolism; PAX6 Transcription Factor; Paired Box Transcription Factors / genetics; Paired Box Transcription Factors / metabolism; Repressor Proteins / genetics; Repressor Proteins / metabolism; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / metabolism; Stem Cell Niche; Transplantation Chimera / embryology; Transplantation Chimera / metabolism
topics (OpenAlex): Neurogenesis and neuroplasticity mechanisms; MicroRNA in disease regulation; RNA Research and Splicing
TL;DR: It is demonstrated that neural stem cells and intermediate neural progenitor cells (NPCs) employ a zinc-finger transcription factor specificity protein 2 (Sp2) as a cell cycle regulator in two temporally and spatially distinct progenitors domains. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2011 article

Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb

Jacquet, B. V., Muthusamy, N., Sommerville, L. J., Xiao, G., Liang, H., Zhang, Y., … Ghashghaei, H. T. (2011, June 22). Journal of Neuroscience.

By: B. Jacquet n, N. Muthusamy n, L. Sommerville n, G. Xiao n, H. Liang n, Y. Zhang *, M. Holtzman *, H. Ghashghaei n

MeSH headings : Animals; Forkhead Transcription Factors / metabolism; Mice; Mice, Knockout; Neurogenesis / physiology; Neurons / physiology; Olfactory Bulb / embryology; Olfactory Bulb / physiology; Prosencephalon / embryology; Prosencephalon / physiology
topics (OpenAlex): Neurogenesis and neuroplasticity mechanisms; Axon Guidance and Neuronal Signaling; Developmental Biology and Gene Regulation
TL;DR: For the first time, this study identifies the time- and region-specific activity of a perinatal progenitor domain that is required for transition and progression of OB neurogenesis from the embryonic-to-postnatal periods. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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