Works (3)
Updated: July 5th, 2023 15:47
2017 journal article
Mosaic analysis with double markers reveals distinct sequential functions of Lgl1 in neural stem cells
Neuron (Cambridge, Mass.), 94(3), 517-.
MeSH headings : Animals; Cell Polarity; Cell Proliferation / genetics; Embryo, Mammalian / metabolism; Glycoproteins / genetics; Glycoproteins / metabolism; Mice; Mice, Knockout; Microscopy, Confocal; Neocortex / embryology; Neocortex / growth & development; Neocortex / pathology; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / genetics; Neuroglia / cytology; Neuroglia / metabolism; Neurons / cytology; Neurons / metabolism
TL;DR:
Results suggest that NSC-mediated neuron and glia production is tightly regulated through the concerted interplay of sequential Lgl1-dependent global and cell intrinsic mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2013 journal article
Neural development is dependent on the function of specificity protein 2 in cell cycle progression
DEVELOPMENT, 140(3), 552–561.
author keywords: Neurogenesis; Neural stem cells; Neural progenitors; Sp2; Cell cycle; M phase; Mouse
MeSH headings : Animals; Brain / cytology; Brain / embryology; Brain / metabolism; Cell Count; Cell Cycle; Cell Proliferation; Crosses, Genetic; Embryo Implantation; Embryo, Mammalian / cytology; Embryo, Mammalian / metabolism; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Eye Proteins / genetics; Eye Proteins / metabolism; Female; Genetic Markers; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Homologous Recombination; Intermediate Filament Proteins / genetics; Intermediate Filament Proteins / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Nestin; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis; Neurons / cytology; Neurons / metabolism; PAX6 Transcription Factor; Paired Box Transcription Factors / genetics; Paired Box Transcription Factors / metabolism; Repressor Proteins / genetics; Repressor Proteins / metabolism; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / metabolism; Stem Cell Niche; Transplantation Chimera / embryology; Transplantation Chimera / metabolism
TL;DR:
It is demonstrated that neural stem cells and intermediate neural progenitor cells (NPCs) employ a zinc-finger transcription factor specificity protein 2 (Sp2) as a cell cycle regulator in two temporally and spatially distinct progenitors domains.
(via Semantic Scholar)
open access via dev.biologists.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb
JOURNAL OF NEUROSCIENCE, 31(25), 9368–9382.
MeSH headings : Animals; Forkhead Transcription Factors / metabolism; Mice; Mice, Knockout; Neurogenesis / physiology; Neurons / physiology; Olfactory Bulb / embryology; Olfactory Bulb / physiology; Prosencephalon / embryology; Prosencephalon / physiology
TL;DR:
For the first time, this study identifies the time- and region-specific activity of a perinatal progenitor domain that is required for transition and progression of OB neurogenesis from the embryonic-to-postnatal periods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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